6j74

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'''Unreleased structure'''
 
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The entry 6j74 is ON HOLD until Paper Publication
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==Complex of GGTaseIII and full-length Ykt6==
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<StructureSection load='6j74' size='340' side='right'caption='[[6j74]], [[Resolution|resolution]] 3.21&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6j74]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J74 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6J74 FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein_geranylgeranyltransferase_type_II Protein geranylgeranyltransferase type II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.60 2.5.1.60] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6j74 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j74 OCA], [http://pdbe.org/6j74 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6j74 RCSB], [http://www.ebi.ac.uk/pdbsum/6j74 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6j74 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/YKT6_HUMAN YKT6_HUMAN]] Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.<ref>PMID:15215310</ref> <ref>PMID:9211930</ref> [[http://www.uniprot.org/uniprot/PGTB2_HUMAN PGTB2_HUMAN]] Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Protein geranylgeranyltransferase type II]]
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[[Category: Fukai, S]]
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[[Category: Goto-Ito, S]]
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[[Category: Sato, Y]]
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[[Category: Yamagata, A]]
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[[Category: Lipid binding protein]]
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[[Category: Lipid transferase]]

Revision as of 16:07, 22 January 2020

Complex of GGTaseIII and full-length Ykt6

PDB ID 6j74

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