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6je7
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human serum albumin crystallized by ammonium sulfate== | |
| - | + | <StructureSection load='6je7' size='340' side='right'caption='[[6je7]], [[Resolution|resolution]] 3.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6je7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JE7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JE7 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6je7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6je7 OCA], [http://pdbe.org/6je7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6je7 RCSB], [http://www.ebi.ac.uk/pdbsum/6je7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6je7 ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Disease == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[http://omim.org/entry/103600 103600]]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fudo, S]] | ||
[[Category: Hoshino, T]] | [[Category: Hoshino, T]] | ||
| - | [[Category: Fudo, S]] | ||
[[Category: Kitahara, M]] | [[Category: Kitahara, M]] | ||
| + | [[Category: Nukaga, M]] | ||
| + | [[Category: Yoneda, T]] | ||
| + | [[Category: Carrier protein]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 06:41, 27 March 2019
Crystal structure of human serum albumin crystallized by ammonium sulfate
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