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6nna

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'''Unreleased structure'''
 
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The entry 6nna is ON HOLD until Paper Publication
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==Human Fatty Acid Synthase Psi/KR Tri-Domain with NADPH and Compound 22==
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<StructureSection load='6nna' size='340' side='right' caption='[[6nna]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
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Authors: Toms, A.V., Martin, M.W.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6nna]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NNA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NNA FirstGlance]. <br>
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Description: Human Fatty Acid Synthase Psi/KR Tri-Domain with NADPH and Compound 22
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=KUA:{4-[4-(1,3-benzoxazol-2-yl)benzene-1-carbonyl]piperazin-1-yl}(1-hydroxycyclopropyl)methanone'>KUA</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAF:S-DIMETHYLARSINOYL-CYSTEINE'>CAF</scene></td></tr>
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[[Category: Martin, M.W]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nna OCA], [http://pdbe.org/6nna PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nna RCSB], [http://www.ebi.ac.uk/pdbsum/6nna PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nna ProSAT]</span></td></tr>
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[[Category: Toms, A.V]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/FAS_HUMAN FAS_HUMAN]] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
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__TOC__
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</StructureSection>
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[[Category: Martin, M W]]
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[[Category: Toms, A V]]
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[[Category: Fatty acid synthase]]
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[[Category: Human fa]]
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[[Category: Keto-reductase]]
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[[Category: Transferase]]

Revision as of 06:55, 21 February 2019

Human Fatty Acid Synthase Psi/KR Tri-Domain with NADPH and Compound 22

6nna, resolution 2.26Å

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