3t62
From Proteopedia
(Difference between revisions)
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==Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Caribbean Sea anemone Stichodactyla helianthus in complex with bovine chymotrypsin== | ==Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Caribbean Sea anemone Stichodactyla helianthus in complex with bovine chymotrypsin== | ||
| - | <StructureSection load='3t62' size='340' side='right' caption='[[3t62]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='3t62' size='340' side='right'caption='[[3t62]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3t62]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3t62]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Stihl Stihl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T62 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Chymotrypsin Chymotrypsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.1 3.4.21.1] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t62 OCA], [https://pdbe.org/3t62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t62 RCSB], [https://www.ebi.ac.uk/pdbsum/3t62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t62 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ISH1_STOHE ISH1_STOHE]] Active against serine, cysteine, and aspartic proteinases. Can bind vertebrate trypsin and chymotrypsin.<ref>PMID:9027993</ref> <ref>PMID:22975140</ref> |
==See Also== | ==See Also== | ||
| - | *[[Chymotrypsin|Chymotrypsin]] | + | *[[Chymotrypsin 3D structures|Chymotrypsin 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Chymotrypsin]] | [[Category: Chymotrypsin]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Stihl]] | [[Category: Stihl]] | ||
[[Category: Betzel, C]] | [[Category: Betzel, C]] | ||
Revision as of 16:44, 6 July 2022
Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Caribbean Sea anemone Stichodactyla helianthus in complex with bovine chymotrypsin
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Categories: Bos taurus | Chymotrypsin | Large Structures | Stihl | Betzel, C | Chavez, M A | Dominguez, R | Garcia-Fernandez, R | Gonzalez-Gonzalez, Y | Oberthuer, D | Pons, T | Redecke, L | Chymotrypsin-inhibitor complex | Hydrolase-hydrolase inhibitor complex | Kunitz-type serine protease inhibitor | Secreted
