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3ovb

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==How the CCA-adding Enzyme Selects Adenine over Cytosine in Position 76 of tRNA==
==How the CCA-adding Enzyme Selects Adenine over Cytosine in Position 76 of tRNA==
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<StructureSection load='3ovb' size='340' side='right' caption='[[3ovb]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='3ovb' size='340' side='right'caption='[[3ovb]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ovb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OVB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ovb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OVB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ouy|3ouy]], [[3ov7|3ov7]], [[3ova|3ova]], [[3ovs|3ovs]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ouy|3ouy]], [[3ov7|3ov7]], [[3ova|3ova]], [[3ovs|3ovs]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ovb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ovb OCA], [http://pdbe.org/3ovb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ovb RCSB], [http://www.ebi.ac.uk/pdbsum/3ovb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ovb ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ovb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ovb OCA], [https://pdbe.org/3ovb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ovb RCSB], [https://www.ebi.ac.uk/pdbsum/3ovb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ovb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CCA_ARCFU CCA_ARCFU]] Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.<ref>PMID:14592988</ref>
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[[https://www.uniprot.org/uniprot/CCA_ARCFU CCA_ARCFU]] Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.<ref>PMID:14592988</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[CCA-adding enzyme|CCA-adding enzyme]]
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*[[CCA-adding enzyme 3D structures|CCA-adding enzyme 3D structures]]
*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Archaeoglobus fulgidus]]
[[Category: Archaeoglobus fulgidus]]
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[[Category: Large Structures]]
[[Category: Pan, B C]]
[[Category: Pan, B C]]
[[Category: Steitz, T A]]
[[Category: Steitz, T A]]

Revision as of 10:58, 18 May 2022

How the CCA-adding Enzyme Selects Adenine over Cytosine in Position 76 of tRNA

PDB ID 3ovb

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