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| | CLP is a heterodimer containing an ATP-binding regulatory subunit A '''ClpA''' or Hsp100 in [[Heat Shock Proteins]] and catalytic subunit P '''ClpP'''. The proteolytic complex is composed of <scene name='50/508398/Cv/2'>2 heptameric rings of ClpP</scene> flanked by hexameric rings of ClpA. For full proteolytic activity ClpP must associate with one of two related ATPase subunits: ClpA and [[ClpX]]. | | CLP is a heterodimer containing an ATP-binding regulatory subunit A '''ClpA''' or Hsp100 in [[Heat Shock Proteins]] and catalytic subunit P '''ClpP'''. The proteolytic complex is composed of <scene name='50/508398/Cv/2'>2 heptameric rings of ClpP</scene> flanked by hexameric rings of ClpA. For full proteolytic activity ClpP must associate with one of two related ATPase subunits: ClpA and [[ClpX]]. |
| - | </StructureSection>
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| | ==3D structures of Clp protease== | | ==3D structures of Clp protease== |
| | + | [[Clp protease 3D structures]] |
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| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
| + | </StructureSection> |
| - | {{#tree:id=OrganizedByTopic|openlevels=0|
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| - | *CLP P subunit
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| - | **[[1tyf]], [[1yg6]] – EcCLP – ''Escherichia coli''<br />
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| - | **[[1yg8]], [[3hln]] - EcCLP (mutant)<br />
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| - | **[[2ds6]] - EcCLP Zinc-binding domain<br />
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| - | **[[1y7o]] – CLP – ''Streptococcus pneumoniae''<br />
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| - | **[[1tg6]] - CLP – human<br />
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| - | **[[2f6i]], [[4gm2]], [[4hnk]] - CLP – ''Plasmodium falciparum''<br />
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| - | **[[2cby]], [[2ce3]], [[2c8t]], [[4u0h]], [[5e0s]], [[5dzk]] - MtCLP – ''Mycobacterium tuberculosis''<br />
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| - | **[[3fes]] - CLP – ''Clostridium difficile''<br />
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| - | **[[3ktg]], [[3kth]], [[3tt6]] – BsCLP – ''Bacillus subtilis''<br />
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| - | **[[3p2l]], [[5g1s]], [[5g1r]], [[5g1q]] - CLP – ''Francisella tulerensis''<br />
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| - | **[[3q7h]] - CLP – ''Coxiella burnetii''<br />
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| - | **[[3qwd]], [[3st9]], [[3sta]], [[3v5e]], [[4emm]], [[4mxi]] - SaCLP – ''Staphylococcus aureus''<br />
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| - | **[[3v5i]], [[4emp]], [[5c90]] - SaCLP (mutant)<br />
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| - | **[[2zl0]] - HpCLP – ''Helicobacter pylori''<br />
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| - | **[[2zl3]] - HpCLP (mutant)<br />
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| - | **[[4jcq]], [[4jct]], [[4ryf]] – LmCLP – ''Listeria monocytogenes''<br />
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| - | **[[4jcr]] - LmCLP (mutant)<br />
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| - | *''CLP P subunit complex''
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| - | **[[2fzs]], [[3mt6]] - EcCLP + peptide<br />
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| - | **[[2zl2]] - HpCLP + peptide<br />
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| - | **[[2zl4]] - HpCLP (mutant) + peptide<br />
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| - | **[[3kti]], [[3ktj]], [[3ktk]] - BsCLP + peptide<br />
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| - | **[[3tt7]] - BsCLP + DFP<br />
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| - | **[[4u0g]] – MtCLP + ADEP + agonist<br />
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| - | **[[5dl1]] – SaCLP + inhibitor<br />
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| - | **[[5dkp]] – CLP + ADEP – ''Neisseria meningitidis''<br />
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| - | *CLP A subunit and CLP N see [[Heat Shock Proteins]] Hsp100
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| - | }} | |
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| | == References == | | == References == |
| | <references/> | | <references/> |
| | [[Category:Topic Page]] | | [[Category:Topic Page]] |
