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6nxf
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of mouse REC114 PH domain in complex with ANKRD31 C terminus== | |
| - | + | <StructureSection load='6nxf' size='340' side='right'caption='[[6nxf]], [[Resolution|resolution]] 2.79Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6nxf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NXF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NXF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nxf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nxf OCA], [http://pdbe.org/6nxf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nxf RCSB], [http://www.ebi.ac.uk/pdbsum/6nxf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nxf ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RE114_MOUSE RE114_MOUSE]] Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination (PubMed:20551173, PubMed:27723721). Probably acts by forming a complex with IHO1/CCDC36 and MEI4, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis (PubMed:27723721).<ref>PMID:20551173</ref> <ref>PMID:27723721</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Patel, D J]] | ||
| + | [[Category: Wang, J]] | ||
| + | [[Category: Ankrd31]] | ||
| + | [[Category: Meiosis]] | ||
| + | [[Category: Nuclear protein]] | ||
| + | [[Category: Rec114]] | ||
Revision as of 07:03, 24 April 2019
Crystal structure of mouse REC114 PH domain in complex with ANKRD31 C terminus
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Categories: Large Structures | Patel, D J | Wang, J | Ankrd31 | Meiosis | Nuclear protein | Rec114
