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6fi9

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Current revision (12:28, 9 May 2024) (edit) (undo)
 
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==Crystal Structure of a zinc-responsive MarR family member, Lactococcus lactis ZitR==
==Crystal Structure of a zinc-responsive MarR family member, Lactococcus lactis ZitR==
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<StructureSection load='6fi9' size='340' side='right' caption='[[6fi9]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='6fi9' size='340' side='right'caption='[[6fi9]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6fi9]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FI9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FI9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6fi9]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_lactis_subsp._cremoris_MG1363 Lactococcus lactis subsp. cremoris MG1363]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FI9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FI9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fi9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fi9 OCA], [http://pdbe.org/6fi9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fi9 RCSB], [http://www.ebi.ac.uk/pdbsum/6fi9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fi9 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6fi9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fi9 OCA], [https://pdbe.org/6fi9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6fi9 RCSB], [https://www.ebi.ac.uk/pdbsum/6fi9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6fi9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ZITR_LACLM ZITR_LACLM]] Zinc-responsive regulator that represses expression of the zit operon in the presence of zinc. Acts by binding two palindromic operator sites overlapping the -35 and -10 boxes of the zit promoter. Could be a sensitive sensor of intracellular zinc to efficiently respond to zinc variations in the environment.<ref>PMID:21317326</ref>
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[https://www.uniprot.org/uniprot/ZITR_LACLM ZITR_LACLM] Zinc-responsive regulator that represses expression of the zit operon in the presence of zinc. Acts by binding two palindromic operator sites overlapping the -35 and -10 boxes of the zit promoter. Could be a sensitive sensor of intracellular zinc to efficiently respond to zinc variations in the environment.<ref>PMID:21317326</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6fi9" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6fi9" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Legrand, P]]
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[[Category: Lactococcus lactis subsp. cremoris MG1363]]
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[[Category: Varela, P F]]
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[[Category: Large Structures]]
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[[Category: Adhesin competence regulator]]
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[[Category: Legrand P]]
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[[Category: Gene regulation]]
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[[Category: Varela PF]]
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[[Category: Multiple antibiotic resistance regulator]]
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[[Category: Winged helix-turn-helix dna binding domain]]
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[[Category: Zinc responsive repressor]]
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[[Category: Zinc transport regulator]]
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Current revision

Crystal Structure of a zinc-responsive MarR family member, Lactococcus lactis ZitR

PDB ID 6fi9

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