4uqg

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==A new bio-isosteric base pair based on reversible bonding==
==A new bio-isosteric base pair based on reversible bonding==
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<StructureSection load='4uqg' size='340' side='right' caption='[[4uqg]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='4uqg' size='340' side='right'caption='[[4uqg]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4uqg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UQG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UQG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4uqg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UQG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UQG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SUC:SUCROSE'>SUC</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene>, <scene name='pdbligand=SAY:[(2R,3S,5R)-3-HYDROXY-5-(3-HYDROXY-4-METHANOYL-PHENYL)OXOLAN-2-YL]METHYL+DIHYDROGEN+PHOSPHATE'>SAY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=T0T:(1R)-1-{4-[(E)-2-(2-AMINOPHENYL)ETHENYL]PHENYL}-1,4-ANHYDRO-2-DEOXY-5-O-PHOSPHONATO-D-ERYTHRO-PENTITOL'>T0T</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAY:[(2R,3S,5R)-3-HYDROXY-5-(3-HYDROXY-4-METHANOYL-PHENYL)OXOLAN-2-YL]METHYL+DIHYDROGEN+PHOSPHATE'>SAY</scene>, <scene name='pdbligand=T0T:(1R)-1-{4-[(E)-2-(2-AMINOPHENYL)ETHENYL]PHENYL}-1,4-ANHYDRO-2-DEOXY-5-O-PHOSPHONATO-D-ERYTHRO-PENTITOL'>T0T</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uqg OCA], [https://pdbe.org/4uqg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uqg RCSB], [https://www.ebi.ac.uk/pdbsum/4uqg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uqg ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uqg OCA], [http://pdbe.org/4uqg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uqg RCSB], [http://www.ebi.ac.uk/pdbsum/4uqg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uqg ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/E1C9K5_GEOSE E1C9K5_GEOSE]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[DNA polymerase|DNA polymerase]]
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 12980]]
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[[Category: Geobacillus stearothermophilus]]
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Large Structures]]
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[[Category: Carell, T]]
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[[Category: Synthetic construct]]
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[[Category: Mueller, M]]
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[[Category: Carell T]]
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[[Category: Serdjukov, S]]
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[[Category: Mueller M]]
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[[Category: Su, M]]
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[[Category: Serdjukov S]]
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[[Category: Tomas-Gamasa, M]]
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[[Category: Su M]]
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[[Category: Transferase-dna complex]]
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[[Category: Tomas-Gamasa M]]
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[[Category: Unnatural base pair]]
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Revision as of 07:32, 29 March 2023

A new bio-isosteric base pair based on reversible bonding

PDB ID 4uqg

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