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5jc3

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Current revision (10:58, 6 September 2023) (edit) (undo)
 
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==Crystal structure of chicken MDA5 with 5'p 10-mer dsRNA and ADP-Mg2+ at 2.6 A resolution (monoclinic form, twinned).==
==Crystal structure of chicken MDA5 with 5'p 10-mer dsRNA and ADP-Mg2+ at 2.6 A resolution (monoclinic form, twinned).==
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<StructureSection load='5jc3' size='340' side='right' caption='[[5jc3]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='5jc3' size='340' side='right'caption='[[5jc3]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5jc3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JC3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JC3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5jc3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JC3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JC3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MDA5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jc3 OCA], [http://pdbe.org/5jc3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jc3 RCSB], [http://www.ebi.ac.uk/pdbsum/5jc3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jc3 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jc3 OCA], [https://pdbe.org/5jc3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jc3 RCSB], [https://www.ebi.ac.uk/pdbsum/5jc3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jc3 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/D9N195_CHICK D9N195_CHICK]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chick]]
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[[Category: Gallus gallus]]
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[[Category: Cusack, S]]
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[[Category: Large Structures]]
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[[Category: Uchikawa, E]]
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[[Category: Synthetic construct]]
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[[Category: Dsrna dependent atpase]]
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[[Category: Cusack S]]
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[[Category: Immune system]]
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[[Category: Uchikawa E]]
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[[Category: Innate immune pattern recognition receptor]]
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[[Category: Rig-i like helicase]]
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[[Category: Zinc-containing ctd domain]]
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Current revision

Crystal structure of chicken MDA5 with 5'p 10-mer dsRNA and ADP-Mg2+ at 2.6 A resolution (monoclinic form, twinned).

PDB ID 5jc3

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