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5mvz
From Proteopedia
(Difference between revisions)
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==Fab 4AB007 bound to Interleukin-1-beta== | ==Fab 4AB007 bound to Interleukin-1-beta== | ||
| - | <StructureSection load='5mvz' size='340' side='right' caption='[[5mvz]], [[Resolution|resolution]] 2.15Å' scene=''> | + | <StructureSection load='5mvz' size='340' side='right'caption='[[5mvz]], [[Resolution|resolution]] 2.15Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5mvz]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5mvz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MVZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MVZ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mvz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mvz OCA], [https://pdbe.org/5mvz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mvz RCSB], [https://www.ebi.ac.uk/pdbsum/5mvz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mvz ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IL1B_HUMAN IL1B_HUMAN] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.<ref>PMID:3920526</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Seibert V]] |
| - | [[Category: | + | [[Category: Stark W]] |
| - | + | ||
| - | + | ||
Current revision
Fab 4AB007 bound to Interleukin-1-beta
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