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3txg
From Proteopedia
(Difference between revisions)
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==HEWL co-crystallization with cisplatin in DMSO media with paratone as the cryoprotectant== | ==HEWL co-crystallization with cisplatin in DMSO media with paratone as the cryoprotectant== | ||
| - | <StructureSection load='3txg' size='340' side='right' caption='[[3txg]], [[Resolution|resolution]] 1.70Å' scene=''> | + | <StructureSection load='3txg' size='340' side='right'caption='[[3txg]], [[Resolution|resolution]] 1.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3txg]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3txg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TXG FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2i6z|2i6z]], [[3txb|3txb]], [[3txc|3txc]], [[3txd|3txd]], [[3txe|3txe]], [[3txf|3txf]], [[3txh|3txh]], [[3txi|3txi]], [[3txj|3txj]], [[3txk|3txk]], [[3txl|3txl]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2i6z|2i6z]], [[3txb|3txb]], [[3txc|3txc]], [[3txd|3txd]], [[3txe|3txe]], [[3txf|3txf]], [[3txh|3txh]], [[3txi|3txi]], [[3txj|3txj]], [[3txk|3txk]], [[3txl|3txl]]</div></td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3txg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3txg OCA], [https://pdbe.org/3txg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3txg RCSB], [https://www.ebi.ac.uk/pdbsum/3txg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3txg ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Lysozyme]] | [[Category: Lysozyme]] | ||
[[Category: Helliwell, J R]] | [[Category: Helliwell, J R]] | ||
Revision as of 05:49, 13 July 2022
HEWL co-crystallization with cisplatin in DMSO media with paratone as the cryoprotectant
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