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Dehalogenase
From Proteopedia
(Difference between revisions)
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In the fluoroacetate dehalogenase complex with halide, the <scene name='59/594596/Cv/5'>iodide is seen in the active site cavity between two tryptophans</scene> (in cyan).<ref>PMID:8369276</ref> | In the fluoroacetate dehalogenase complex with halide, the <scene name='59/594596/Cv/5'>iodide is seen in the active site cavity between two tryptophans</scene> (in cyan).<ref>PMID:8369276</ref> | ||
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| + | ==3D structures of dehalogenase== | ||
| + | [[Dehalogenase 3D structures]] | ||
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</StructureSection> | </StructureSection> | ||
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**[[3a2l]] – BjHLD DbjA (mutant) + Cl <br /> | **[[3a2l]] – BjHLD DbjA (mutant) + Cl <br /> | ||
**[[5esr]] – HLD DccA + Cl – ''Caulobacter crescentus''<br /> | **[[5esr]] – HLD DccA + Cl – ''Caulobacter crescentus''<br /> | ||
| + | **[[6f9o]] – HLD + Cl – ''Psychrobacter cryohalolentis''<br /> | ||
*Fluoroacetate dehalogenase (FDH) | *Fluoroacetate dehalogenase (FDH) | ||
**[[1y37]] – BuFDH – ''Burkholderia''<br /> | **[[1y37]] – BuFDH – ''Burkholderia''<br /> | ||
| - | **[[3r3u]], [[5nyv]], [[5k3d]], [[5k3c]] – RpFDH – ''Rhodopseudomonas palustris''<br /> | + | **[[3r3u]], [[5nyv]], [[5k3d]], [[5k3c]], [[6gxh]], [[6gxl]], [[6muh]], [[6muy]], [[6mzz]], [[6n00]], [[6fsx]], [[5o2i]], [[5o2g]] – RpFDH – ''Rhodopseudomonas palustris''<br /> |
**[[3r40]], [[3r41]], [[5t4t]], [[5k3f]], [[5k3e]] – RpFDH (mutant) <br /> | **[[3r40]], [[3r41]], [[5t4t]], [[5k3f]], [[5k3e]] – RpFDH (mutant) <br /> | ||
*''Fluoroacetate dehalogenase complexes'' | *''Fluoroacetate dehalogenase complexes'' | ||
| + | **[[6gxd]], [[6gxf]], [[6gxt]] – RpFDH + fluoroacetate<br /> | ||
**[[3r3v]], [[3r3y]], [[5swn]], [[5k3a]] – RpFDH (mutant) + fluoroacetate<br /> | **[[3r3v]], [[3r3y]], [[5swn]], [[5k3a]] – RpFDH (mutant) + fluoroacetate<br /> | ||
**[[5k3c]] – RpFDH + fluorotryptophan<br /> | **[[5k3c]] – RpFDH + fluorotryptophan<br /> | ||
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**[[4ttb]] – hITDH 1 + FMN<br /> | **[[4ttb]] – hITDH 1 + FMN<br /> | ||
**[[4ttc]] – hITDH 1 + FMN + iodotyrosine <br /> | **[[4ttc]] – hITDH 1 + FMN + iodotyrosine <br /> | ||
| + | **[[5yak]] – hITDH 1 (mutant) + FMN + fluorotyrosine <br /> | ||
*cis-3-chloroacrylic acid dehalogenase (CaaD) | *cis-3-chloroacrylic acid dehalogenase (CaaD) | ||
Revision as of 06:42, 5 June 2019
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3D structures of dehalogenase
Updated on 05-June-2019
References
- ↑ Koudelakova T, Chovancova E, Brezovsky J, Monincova M, Fortova A, Jarkovsky J, Damborsky J. Substrate specificity of haloalkane dehalogenases. Biochem J. 2011 Apr 15;435(2):345-54. doi: 10.1042/BJ20101405. PMID:21294712 doi:http://dx.doi.org/10.1042/BJ20101405
- ↑ Verschueren KH, Kingma J, Rozeboom HJ, Kalk KH, Janssen DB, Dijkstra BW. Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site. Biochemistry. 1993 Sep 7;32(35):9031-7. PMID:8369276
