Dehydroquinase
From Proteopedia
(Difference between revisions)
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The structure of dehydroquinase type I complex with quinate shows <scene name='55/553960/Cv/10'>DHQD as a homodimer</scene>. The binding of quinate in <scene name='55/553960/Cv/11'>monomer A is slightly different than in monomer B</scene>.<ref>PMID:24437575</ref> <scene name='55/553960/Cv/12'>Click here to see the animation of this scene</scene>. | The structure of dehydroquinase type I complex with quinate shows <scene name='55/553960/Cv/10'>DHQD as a homodimer</scene>. The binding of quinate in <scene name='55/553960/Cv/11'>monomer A is slightly different than in monomer B</scene>.<ref>PMID:24437575</ref> <scene name='55/553960/Cv/12'>Click here to see the animation of this scene</scene>. | ||
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| + | ==3D structures of dehydroquinase== | ||
| + | [[Dehydroquinase 3D structures]] | ||
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</StructureSection> | </StructureSection> | ||
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**[[4uio]] – DHQD + dehydroquinic acid derivative – ''Salmonella enterica''<br /> | **[[4uio]] – DHQD + dehydroquinic acid derivative – ''Salmonella enterica''<br /> | ||
| - | *DHQD-II | + | *DHQD-II or 3-dehydroquinate dehydratase |
**[[1d0i]], [[1gu0]] – ScDHQD – ''Streptomyces coelicolor'' <br /> | **[[1d0i]], [[1gu0]] – ScDHQD – ''Streptomyces coelicolor'' <br /> | ||
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**[[3u80]] – DHQD – ''Bifidobacterium longum'' <br /> | **[[3u80]] – DHQD – ''Bifidobacterium longum'' <br /> | ||
**[[4l8l]] – DHQD – ''Pseudomonas aeruginosa'' <br /> | **[[4l8l]] – DHQD – ''Pseudomonas aeruginosa'' <br /> | ||
| - | **[[4rc9]], [[4rhc]], [[4zc1]], [[5b6p]], [[5wrf]], [[5x47]] – | + | **[[4rc9]], [[4rhc]], [[4zc1]], [[5b6p]], [[5wrf]], [[5x47]], [[5yhm]], [[5yl5]], [[5ypq]] – AbDHQD – ''Acinetobacter baumannii''<br /> |
| + | **[[6cv6]] – DHQD – ''Paraburkholderia phymatum''<br /> | ||
*DHQD-II complexes | *DHQD-II complexes | ||
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**[[4cky]], [[4cl0]] – MtDHQD + dehydroquinic acid derivative<br /> | **[[4cky]], [[4cl0]] – MtDHQD + dehydroquinic acid derivative<br /> | ||
**[[4v0s]] – MtDHQD (mutant) + dehydroquinic acid derivative<br /> | **[[4v0s]] – MtDHQD (mutant) + dehydroquinic acid derivative<br /> | ||
| + | **[[5ydb]] – AbDHQD + dehydroquinic acid derivative<br /> | ||
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 08:24, 5 June 2019
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3D structures of dehydroquinase
Updated on 05-June-2019
References
- ↑ Herrmann KM. The Shikimate Pathway: Early Steps in the Biosynthesis of Aromatic Compounds. Plant Cell. 1995 Jul;7(7):907-919. PMID:12242393 doi:http://dx.doi.org/10.1105/tpc.7.7.907
- ↑ Dias MV, Snee WC, Bromfield KM, Payne R, Palaninathan SK, Ciulli A, Howard NI, Abell C, Sacchettini JC, Blundell TL. Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis. Biochem J. 2011 Mar 17. PMID:21410435 doi:10.1042/BJ20110002
- ↑ Light SH, Antanasijevic A, Krishna SN, Caffrey M, Anderson WF, Lavie A. Crystal structures of type I dehydroquinate dehydratase in complex with quinate and shikimate suggest a novel mechanism of Schiff base formation. Biochemistry. 2014 Feb 11;53(5):872-80. doi: 10.1021/bi4015506. Epub 2014 Jan 31. PMID:24437575 doi:http://dx.doi.org/10.1021/bi4015506
