DNA glycosylase

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*<scene name='44/445369/Cv/11'>Fe4S4 cluster binds to 3 Cys residues</scene>.
*<scene name='44/445369/Cv/11'>Fe4S4 cluster binds to 3 Cys residues</scene>.
*<scene name='44/445369/Cv/12'>Ca+2 ion coordination site</scene> (PDB code [[1rrs]])<ref>PMID:14961129</ref>. Water molecules shown as red spheres.
*<scene name='44/445369/Cv/12'>Ca+2 ion coordination site</scene> (PDB code [[1rrs]])<ref>PMID:14961129</ref>. Water molecules shown as red spheres.
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== 3D Structures of DNA glycosylase ==
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[[DNA glycosylase 3D structures]]
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</StructureSection>
</StructureSection>
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== 3D Structures of DNA glycosylate ==
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== 3D Structures of DNA glycosylase ==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}

Revision as of 10:21, 11 June 2019

Structure of adenine DNA glycosylase containing Fe4S4 cluster complex with DNA containing an oxoG base, deoxy-ribofuranose phosphate and Ca+2 ion (green) (PDB code 1rrs).

Drag the structure with the mouse to rotate

3D Structures of DNA glycosylase

Updated on 11-June-2019


References

  1. Fromme JC, Banerjee A, Verdine GL. DNA glycosylase recognition and catalysis. Curr Opin Struct Biol. 2004 Feb;14(1):43-9. PMID:15102448 doi:http://dx.doi.org/10.1016/j.sbi.2004.01.003
  2. Willetts KE, Rey F, Agostini I, Navarro JM, Baudat Y, Vigne R, Sire J. DNA repair enzyme uracil DNA glycosylase is specifically incorporated into human immunodeficiency virus type 1 viral particles through a Vpr-independent mechanism. J Virol. 1999 Feb;73(2):1682-8. PMID:9882380
  3. Fromme JC, Banerjee A, Huang SJ, Verdine GL. Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase. Nature. 2004 Feb 12;427(6975):652-6. PMID:14961129 doi:10.1038/nature02306

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