6qpq
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The structure of the cohesin head module elucidates the mechanism of ring opening== |
| - | + | <StructureSection load='6qpq' size='340' side='right'caption='[[6qpq]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6qpq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QPQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QPQ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qpq OCA], [http://pdbe.org/6qpq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qpq RCSB], [http://www.ebi.ac.uk/pdbsum/6qpq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qpq ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SCC1_YEAST SCC1_YEAST]] Cleavable component of the cohesin complex involved in chromosome cohesion during cell cycle. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by ESP1 and dissociates from chromatin, allowing sister chromatids to segregate.<ref>PMID:9335333</ref> <ref>PMID:9335334</ref> <ref>PMID:9491073</ref> <ref>PMID:10403247</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Li, Y]] | ||
| + | [[Category: Muir, K W]] | ||
| + | [[Category: Panne, D]] | ||
| + | [[Category: Cell cycle]] | ||
| + | [[Category: Cell division]] | ||
| + | [[Category: Cohesin]] | ||
| + | [[Category: Genome regulation]] | ||
| + | [[Category: Kleisin]] | ||
| + | [[Category: Sister chromatid cohesion]] | ||
| + | [[Category: Smc]] | ||
Revision as of 08:06, 5 February 2020
The structure of the cohesin head module elucidates the mechanism of ring opening
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