3zl1
From Proteopedia
(Difference between revisions)
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==A thiazolyl-mannoside bound to FimH, monoclinic space group== | ==A thiazolyl-mannoside bound to FimH, monoclinic space group== | ||
- | <StructureSection load='3zl1' size='340' side='right' caption='[[3zl1]], [[Resolution|resolution]] 1.55Å' scene=''> | + | <StructureSection load='3zl1' size='340' side='right'caption='[[3zl1]], [[Resolution|resolution]] 1.55Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3zl1]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3zl1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_j96 Escherichia coli j96]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZL1 FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BWG:N-{5-[(1R)-1-HYDROXYETHYL]-1,3-THIAZOL-2-YL}-ALPHA-D-MANNOPYRANOSYLAMINE'>BWG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BWG:N-{5-[(1R)-1-HYDROXYETHYL]-1,3-THIAZOL-2-YL}-ALPHA-D-MANNOPYRANOSYLAMINE'>BWG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> |
- | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zl2|3zl2]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zl2|3zl2]]</div></td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zl1 OCA], [https://pdbe.org/3zl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zl1 RCSB], [https://www.ebi.ac.uk/pdbsum/3zl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zl1 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
- | *[[Adhesin|Adhesin]] | + | *[[Adhesin 3D structures|Adhesin 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli j96]] | [[Category: Escherichia coli j96]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Bilyy, R O]] | [[Category: Bilyy, R O]] | ||
[[Category: Bouckaert, J]] | [[Category: Bouckaert, J]] |
Revision as of 05:50, 10 August 2022
A thiazolyl-mannoside bound to FimH, monoclinic space group
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Categories: Escherichia coli j96 | Large Structures | Bilyy, R O | Bouckaert, J | Brument, S | Chalopin, T | Darfeuille-Michaud, A | Deniaud, D | Dumych, T I | Gouin, S G | Guerardel, Y | Moreau, N | Roos, G | Sivignon, A | Cell adhesion | Crohn's disease | Immunoglobulin | Thiazole | Type-1 fimbriae