3zyi
From Proteopedia
(Difference between revisions)
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==NetrinG2 in complex with NGL2== | ==NetrinG2 in complex with NGL2== | ||
- | <StructureSection load='3zyi' size='340' side='right' caption='[[3zyi]], [[Resolution|resolution]] 2.60Å' scene=''> | + | <StructureSection load='3zyi' size='340' side='right'caption='[[3zyi]], [[Resolution|resolution]] 2.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3zyi]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3zyi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZYI FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
- | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zyg|3zyg]], [[2dl9|2dl9]], [[3zyj|3zyj]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zyg|3zyg]], [[2dl9|2dl9]], [[3zyj|3zyj]]</div></td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zyi OCA], [https://pdbe.org/3zyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zyi RCSB], [https://www.ebi.ac.uk/pdbsum/3zyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zyi ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/LRRC4_HUMAN LRRC4_HUMAN]] Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays a important role for auditory synaptic responses. Involved in the suppression of glioma (By similarity). [[https://www.uniprot.org/uniprot/NTNG2_HUMAN NTNG2_HUMAN]] Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites.<ref>PMID:21946559</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Aricescu, A R]] | [[Category: Aricescu, A R]] | ||
[[Category: Coles, C H]] | [[Category: Coles, C H]] |
Revision as of 07:28, 18 August 2022
NetrinG2 in complex with NGL2
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