User:Kristian Koski/P4H
From Proteopedia
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<StructureSection load='3gze' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='3gze' size='340' side='right' caption='Caption for this structure' scene=''> | ||
Chlamydomonas reinhardtii prolyl 4-hydroxylase is a monomeric enzyme which catalyse the hydroxylation of proline residues of the proline-rich cell wall proteins. The structure of Cr-P4H has been determined as apo and in complexed with Zinc and serine-proline rich peptide<ref>pmid 19553701</ref>. | Chlamydomonas reinhardtii prolyl 4-hydroxylase is a monomeric enzyme which catalyse the hydroxylation of proline residues of the proline-rich cell wall proteins. The structure of Cr-P4H has been determined as apo and in complexed with Zinc and serine-proline rich peptide<ref>pmid 19553701</ref>. | ||
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== Function ==http://proteopedia.org/wiki/index.php?title=User:Kristian_Koski/P4H&action=edit | == Function ==http://proteopedia.org/wiki/index.php?title=User:Kristian_Koski/P4H&action=edit | ||
Prolyl 4-hydroxylase (P4H) catalyses the hydroxylation of a proline resiue in the collagens . | Prolyl 4-hydroxylase (P4H) catalyses the hydroxylation of a proline resiue in the collagens . | ||
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P4H belongs to the super family of 2-oxoglutarate dioxygenases. | P4H belongs to the super family of 2-oxoglutarate dioxygenases. | ||
== Structural highlights == | == Structural highlights == | ||
| + | Two <scene name='80/809814/Morph-test/1'>flexible loops</scene>. | ||
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
Revision as of 12:49, 28 February 2019
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References
- ↑ Koski MK, Hieta R, Hirsila M, Ronka A, Myllyharju J, Wierenga RK. The crystal structure of an algal prolyl 4-hydroxylase complexed with a proline-rich peptide reveals a novel buried tripeptide binding motif. J Biol Chem. 2009 Sep 11;284(37):25290-301. Epub 2009 Jun 24. PMID:19553701 doi:10.1074/jbc.M109.014050
