Alanine racemase

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Current revision (11:27, 3 March 2019) (edit) (undo)
 
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== 3D Structures of alanine racemase ==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*Alanine racemase
 
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**[[3uw6]] – GsAR – ''Geobacillus stearothermophilus'' <BR />
 
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**[[3hur]] – OoAR - ''Oenococcus oeni''<BR />
 
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**[[3oo2]], [[6g56]] – SaAR - ''Staphyloococcus aureus''<BR />
 
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**[[4bhy]] – AhAR – ''Aeromonas hydrophila''<br />
 
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**[[3c3k]] – AR – ''Actinobacillus succinogenes''<br />
 
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**[[4xbj]] - EcAR (mutant) - ''Escherichia coli''<br />
 
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**[[5irp]] – AR 2 – ''Bacillus subtilis''<br />
 
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*Alanine racemase complexes containing PLP
 
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**[[1sft]] – GsAR + PLP <BR />
 
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**[[2sfp]] – GsAR + PLP + propionate inhibitor <BR />
 
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**[[1l6f]], [[1l6g]] – GsAR + PLP-alanine <BR />
 
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**[[1xqk]] – GsAR (mutant) + PLP derivative <BR />
 
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**[[1xql]] – GsAR (mutant) + PLP + pyridoxamine phosphate + pyridoxamine phosphate hydroxyisoxazole<BR />
 
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**[[1vfh]] – SlAR + PLP – ''Streptomyces lavendulae'' <BR />
 
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**[[1xfc]] – AR + PLP – ''Mycobacterium tuberculosis'' <BR />
 
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**[[2dy3]] – AR + PLP – ''Corynebacterium glutamicum'' <BR />
 
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**[[5yyc]] – AR + PLP – ''Bacillus pseudofirmus'' <BR />
 
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**[[3ha1]] – BaAR + lysine-PLP <BR />
 
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**[[3kw3]] – AR + lysine-PLP - ''Bartonella henselae''<BR />
 
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**[[3s46]] – AR + lysine-PLP - ''Streptococcus pneumoniae''<BR />
 
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**[[1rcq]], [[6a2f]] – AR + PLP derivative - ''Pseudomonas aeruginosa''<BR />
 
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**[[2odo]] – AR + lysine-PLP - ''Pseudomonas fluorescens''<BR />
 
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**[[2rjg]] – EcAR + PLP <BR />
 
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**[[3b8t]], [[3b8u]], [[3b8v]], [[3b8w]], [[4wr3]] – EcAR (mutant) + PLP<br />
 
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**[[3co8]] – OoAR + PLP <BR />
 
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**[[4a3q]], [[6g58]], [[6g59]] – SaAR + PLP derivative <BR />
 
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**[[3e5p]] – EfAR + PLP - ''Enterococcus faecalis''<BR />
 
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**[[4beu]] – VcAR + PLP – ''Vibrio cholerae''<br />
 
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**[[4beq]] – VcAR (mutant) + PLP <br />
 
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**[[4bf5]] – AhAR + PLP <br />
 
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**[[4qhr]] – AbCdAR + PLP – ''Acinetobacter baumanii''<br />
 
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**[[4qhr]] – AbCdAR + PLP derivative <br />
 
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**[[4lus]] – CdAR + PLP derivative – ''Clostridium difficile''<br />
 
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**[[4luy]] – CdAR (mutant) + PLP derivative + cycloserine<br />
 
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**[[4lut]] – CdAR + PLP derivative + cycloserine<br />
 
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**[[5fac]] – ScAR + PLP – ''Streptomyces coelicolor''<br />
 
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**[[5fag]] – ScAR + PLP + inhibitor<br />
 
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**[[5faj]] – ScAR + PLP + cycloserine<br />
 
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*Alanine racemase complexes not containing PLP
 
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**[[1bd0]], [[1ftx]] – GsAR + alanine phosphonate <BR />
 
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**[[1epv]], [[1niu]] – GsAR + cycloserine inhibitor <BR />
 
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**[[2rjh]] – EcAR + cycloserine inhibitor <BR />
 
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**[[3e6e]] – EfAR + cycloserine inhibitor <BR />
 
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**[[1vfs]], [[1vft]] – SlAR + cycloserine inhibitor <BR />
 
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**[[4beq]] – VcAR (mutant) + PLP <br />
 
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**[[4y2w]] – AR + alanine – ''Caldanaerobacter tencongensis'' <BR />
 
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**[[2vd8]], [[2vd9]] – BaAR + inhibitor – ''Bacillus anthracis'' <BR />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category: Topic Page]]
[[Category: Topic Page]]

Current revision

Structure of alanine racemase dimer complex with phosphopyridoxyl-alanine (in magenta) (PDB entry 1l6g)

Drag the structure with the mouse to rotate

References

  1. 1.0 1.1 Watanabe A, Yoshimura T, Mikami B, Hayashi H, Kagamiyama H, Esaki N. Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine. J Biol Chem. 2002 May 24;277(21):19166-72. Epub 2002 Mar 8. PMID:11886871 doi:10.1074/jbc.M201615200

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Michal Harel, Alexander Berchansky

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