5zyi
From Proteopedia
(Difference between revisions)
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==Crystal structure of CERT START domain in complex with compound E16== | ==Crystal structure of CERT START domain in complex with compound E16== | ||
| - | <StructureSection load='5zyi' size='340' side='right' | + | <StructureSection load='5zyi' size='340' side='right'caption='[[5zyi]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5zyi]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5zyi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZYI FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9ML:2-[4-[4-pentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol'>9ML</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9ML:2-[4-[4-pentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol'>9ML</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zyi OCA], [https://pdbe.org/5zyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zyi RCSB], [https://www.ebi.ac.uk/pdbsum/5zyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zyi ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] The disease is caused by variants affecting the gene represented in this entry. | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Egawa | + | [[Category: Large Structures]] |
| - | [[Category: Hanada | + | [[Category: Egawa D]] |
| - | [[Category: Hanzawa | + | [[Category: Hanada K]] |
| - | [[Category: Kawasaki | + | [[Category: Hanzawa H]] |
| - | [[Category: Kobayashi | + | [[Category: Kawasaki S]] |
| - | [[Category: Kumagai | + | [[Category: Kobayashi S]] |
| - | [[Category: Nakao | + | [[Category: Kumagai K]] |
| - | [[Category: Sakai | + | [[Category: Nakao N]] |
| - | [[Category: Suzuki | + | [[Category: Sakai S]] |
| - | [[Category: Ueno | + | [[Category: Suzuki M]] |
| - | + | [[Category: Ueno M]] | |
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Current revision
Crystal structure of CERT START domain in complex with compound E16
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Categories: Homo sapiens | Large Structures | Egawa D | Hanada K | Hanzawa H | Kawasaki S | Kobayashi S | Kumagai K | Nakao N | Sakai S | Suzuki M | Ueno M
