4aed
From Proteopedia
(Difference between revisions)
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<StructureSection load='4aed' size='340' side='right'caption='[[4aed]], [[Resolution|resolution]] 3.80Å' scene=''> | <StructureSection load='4aed' size='340' side='right'caption='[[4aed]], [[Resolution|resolution]] 3.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4aed]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4aed]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_enterovirus_71 Human enterovirus 71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AED OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AED FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4aed FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aed OCA], [https://pdbe.org/4aed PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4aed RCSB], [https://www.ebi.ac.uk/pdbsum/4aed PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4aed ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/A9X4C2_9ENTO A9X4C2_9ENTO]] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS000199_004_016611] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047] |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 4aed" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4aed" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human enterovirus 71]] | [[Category: Human enterovirus 71]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Kuhn, R J]] | [[Category: Kuhn, R J]] | ||
[[Category: Perera, R]] | [[Category: Perera, R]] | ||
Revision as of 05:31, 25 August 2022
Crystal structure of Human enterovirus 71
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