4a6l

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<StructureSection load='4a6l' size='340' side='right'caption='[[4a6l]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='4a6l' size='340' side='right'caption='[[4a6l]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4a6l]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A6L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A6L FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4a6l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A6L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A6L FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=P43:1-{3-[1-({5-[(2-FLUOROPHENYL)ETHYNYL]FURAN-2-YL}CARBONYL)PIPERIDIN-4-YL]PHENYL}METHANAMINE'>P43</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P43:1-{3-[1-({5-[(2-FLUOROPHENYL)ETHYNYL]FURAN-2-YL}CARBONYL)PIPERIDIN-4-YL]PHENYL}METHANAMINE'>P43</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1aao|1aao]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1aao|1aao]]</div></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptase Tryptase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.59 3.4.21.59] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Tryptase Tryptase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.59 3.4.21.59] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a6l OCA], [http://pdbe.org/4a6l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4a6l RCSB], [http://www.ebi.ac.uk/pdbsum/4a6l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4a6l ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a6l OCA], [https://pdbe.org/4a6l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a6l RCSB], [https://www.ebi.ac.uk/pdbsum/4a6l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a6l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TRYB1_HUMAN TRYB1_HUMAN]] Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type (By similarity).
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[[https://www.uniprot.org/uniprot/TRYB1_HUMAN TRYB1_HUMAN]] Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Tryptase]]
[[Category: Tryptase]]
[[Category: Maignan, S]]
[[Category: Maignan, S]]

Revision as of 07:48, 18 August 2022

beta-tryptase inhibitor

PDB ID 4a6l

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