Aminoacyl tRNA synthetase 3D structures
From Proteopedia
(Difference between revisions)
| Line 7: | Line 7: | ||
*Class I aaRS | *Class I aaRS | ||
| - | *Arg-RS | + | *'''Arg-RS''' |
**[[4zaj]] - hArgRS – human<br /> | **[[4zaj]] - hArgRS – human<br /> | ||
| Line 33: | Line 33: | ||
**[[2zue]] – PhArgRS + tRNA-Arg + ATP analog<br /> | **[[2zue]] – PhArgRS + tRNA-Arg + ATP analog<br /> | ||
| - | *Cys-RS | + | *'''Cys-RS''' |
**[[1li5]] - EcCysRS <br /> | **[[1li5]] - EcCysRS <br /> | ||
| Line 42: | Line 42: | ||
**[[3c8z]] – MsCysRS + Cys-SA - ''Mycobacterium smegmatis''<br /> | **[[3c8z]] – MsCysRS + Cys-SA - ''Mycobacterium smegmatis''<br /> | ||
| - | *Gln-RS | + | *'''Gln-RS''' |
**[[4ye6]] – hGlnRS <br /> | **[[4ye6]] – hGlnRS <br /> | ||
| Line 62: | Line 62: | ||
**[[1qtq]] - EcGlnRS + Gln-tRNA + Gln analog<br /> | **[[1qtq]] - EcGlnRS + Gln-tRNA + Gln analog<br /> | ||
| - | *Glu-RS | + | *'''Glu-RS''' |
**[[2hra]] – yGluRS N-terminal<br /> | **[[2hra]] – yGluRS N-terminal<br /> | ||
| Line 102: | Line 102: | ||
**[[2cv2]] - TtGluRS + Glu-SA + Glu-tRNA<br /> | **[[2cv2]] - TtGluRS + Glu-SA + Glu-tRNA<br /> | ||
| - | *Ile-RS | + | *'''Ile-RS''' |
**[[1ile]] - TtIleRS<br /> | **[[1ile]] - TtIleRS<br /> | ||
| Line 117: | Line 117: | ||
**[[1ffy]], [[1qu2]], [[1qu3]] - SaIleRS + Ile-tRNA + antibiotic - ''Staphylococcus aureus''<br /> | **[[1ffy]], [[1qu2]], [[1qu3]] - SaIleRS + Ile-tRNA + antibiotic - ''Staphylococcus aureus''<br /> | ||
| - | *Leu-RS | + | *'''Leu-RS''' |
**[[2wfd]] – hLeuRS editing domain<br /> | **[[2wfd]] – hLeuRS editing domain<br /> | ||
| Line 165: | Line 165: | ||
**[[2v0c]] – TtLeuRS + Leu-SA + benzoxaborole-AMP<br /> | **[[2v0c]] – TtLeuRS + Leu-SA + benzoxaborole-AMP<br /> | ||
| - | *Lys-RS | + | *'''Lys-RS''' |
**[[3bju]] – hLysRS residues 70-579<br /> | **[[3bju]] – hLysRS residues 70-579<br /> | ||
| Line 209: | Line 209: | ||
**[[6aqh]] - LysRS + Lys + cladosporin – ''Mycobacterium thermoresistibile''<br /> | **[[6aqh]] - LysRS + Lys + cladosporin – ''Mycobacterium thermoresistibile''<br /> | ||
| - | *Met-RS | + | *'''Met-RS''' |
**[[5gl7]] – hMetRS residues 221-834<br /> | **[[5gl7]] – hMetRS residues 221-834<br /> | ||
| Line 258: | Line 258: | ||
**[[2hsn]] - yMetRS N-terminal + GU4 nucleic-binding protein 1 N-terminal<br /> | **[[2hsn]] - yMetRS N-terminal + GU4 nucleic-binding protein 1 N-terminal<br /> | ||
| - | *Trp-RS | + | *'''Trp-RS''' |
**[[1o5t]], [[1ulh]] – hTrpRS catalytic fragment<br /> | **[[1o5t]], [[1ulh]] – hTrpRS catalytic fragment<br /> | ||
| Line 308: | Line 308: | ||
**[[5v0i]] - EcTrpRS + Trp + AMP<br /> | **[[5v0i]] - EcTrpRS + Trp + AMP<br /> | ||
| - | + | * ''Trp-RS + tRNA'' | |
**[[2ake]], [[2dr2]] - hTrpRS + Trp-tRNA<br /> | **[[2ake]], [[2dr2]] - hTrpRS + Trp-tRNA<br /> | ||
**[[2azx]] – hTrpRS (mutant) + tRNA<br /> | **[[2azx]] – hTrpRS (mutant) + tRNA<br /> | ||
| - | *Tyr-RS | + | *'''Tyr-RS''' |
**[[1n3l]] - hTyrRS <br /> | **[[1n3l]] - hTyrRS <br /> | ||
| Line 368: | Line 368: | ||
**[[2rkj]] – NcTyrRS + RNA<br /> | **[[2rkj]] – NcTyrRS + RNA<br /> | ||
| - | *3-nitroTyr-RS | + | *'''3-nitroTyr-RS''' |
**[[4nd6]], [[4nd7]] - MjNTyrRS (mutant)<br /> | **[[4nd6]], [[4nd7]] - MjNTyrRS (mutant)<br /> | ||
**[[4nda]] - MjNTyrRS (mutant) + nitro-Tyr<br /> | **[[4nda]] - MjNTyrRS (mutant) + nitro-Tyr<br /> | ||
| - | *Val-RS | + | *'''Val-RS''' |
**[[4xkz]] - hLysRS C-terminal<br /> | **[[4xkz]] - hLysRS C-terminal<br /> | ||
| Line 384: | Line 384: | ||
*Class II aaRS | *Class II aaRS | ||
| - | *Ala-RS | + | *'''Ala-RS''' |
**[[5t76]], [[4xem]] - hAlaRS catalytic domain<br /> | **[[5t76]], [[4xem]] - hAlaRS catalytic domain<br /> | ||
| Line 412: | Line 412: | ||
**[[3wqy]], [[3wqz]] – AfAlaRS + Ala-tRNA + Ala-SA<br /> | **[[3wqy]], [[3wqz]] – AfAlaRS + Ala-tRNA + Ala-SA<br /> | ||
| - | *Asp-RS | + | *'''Asp-RS''' |
**[[4j15]], [[4ah6]] - hAspRS <br /> | **[[4j15]], [[4ah6]] - hAspRS <br /> | ||
| Line 442: | Line 442: | ||
**[[4wj3]] – PaAspRS + Asn-tRNA + amidotransferase<br /> | **[[4wj3]] – PaAspRS + Asn-tRNA + amidotransferase<br /> | ||
| - | *Asn-RS | + | *'''Asn-RS''' |
**[[5xix]] - hAsnRS <br /> | **[[5xix]] - hAsnRS <br /> | ||
| Line 458: | Line 458: | ||
**[[3rl6]] - PaAsnRS + Asn + AMP<br /> | **[[3rl6]] - PaAsnRS + Asn + AMP<br /> | ||
| - | *Gly-RS | + | *'''Gly-RS''' |
**[[2q5h]] – hGlyRS residues 55-739<br /> | **[[2q5h]] – hGlyRS residues 55-739<br /> | ||
| Line 483: | Line 483: | ||
**[[4kr3]] - hGlyRS (mutant) + Gly-tRNA<br /> | **[[4kr3]] - hGlyRS (mutant) + Gly-tRNA<br /> | ||
| - | *His-RS | + | *'''His-RS''' |
**[[4x5o]], [[4g84]], [[4g85]] - hHisRS <br /> | **[[4x5o]], [[4g84]], [[4g85]] - hHisRS <br /> | ||
| Line 513: | Line 513: | ||
**[[4e51]] - BtHisRS + His <br /> | **[[4e51]] - BtHisRS + His <br /> | ||
| - | *Phe-RS | + | *'''Phe-RS''' |
**[[3l4g]], [[3cmq]] – hPheRS<br /> | **[[3l4g]], [[3cmq]] – hPheRS<br /> | ||
| Line 536: | Line 536: | ||
**[[4p72]], [[4p73]], [[4p74]], [[4p75]] – PaPheRS + chains + inhibitor<br /> | **[[4p72]], [[4p73]], [[4p74]], [[4p75]] – PaPheRS + chains + inhibitor<br /> | ||
| - | |||
* ''Phe-RS + tRNA'' | * ''Phe-RS + tRNA'' | ||
**[[3tup]] – hPheRS + Phe-tRNA<br /> | **[[3tup]] – hPheRS + Phe-tRNA<br /> | ||
| Line 542: | Line 541: | ||
**[[2iy5]] - TtPheRS + chains + Phe-ol + Phe-tRNA<br /> | **[[2iy5]] - TtPheRS + chains + Phe-ol + Phe-tRNA<br /> | ||
| - | + | *'''Pro-RS''' | |
| - | *Pro-RS | + | |
**[[4k86]] – hProRS residues 1000-1512 <br /> | **[[4k86]] – hProRS residues 1000-1512 <br /> | ||
| Line 580: | Line 578: | ||
**[[4ydq]], [[4q15]], [[4olf]] – PfProRS residues 254-746 + halofuginone + AMPPNP <br /> | **[[4ydq]], [[4q15]], [[4olf]] – PfProRS residues 254-746 + halofuginone + AMPPNP <br /> | ||
| - | *Bifunctional RS (bifunctional glutamate/proline tRNA ligase) | + | *'''Bifunctional RS''' (bifunctional glutamate/proline tRNA ligase) |
**[[4hvc]] – hEPRS residues 1003-1513 + halofunginone + ATP analog<br /> | **[[4hvc]] – hEPRS residues 1003-1513 + halofunginone + ATP analog<br /> | ||
| Line 587: | Line 585: | ||
**[[5a1n]], [[5a34]], [[5a5h]] – hEPRS GST-like domain + EPRS-AIMP2<br /> | **[[5a1n]], [[5a34]], [[5a5h]] – hEPRS GST-like domain + EPRS-AIMP2<br /> | ||
| - | *Pyrrolysyl-RS; domains – RNA-binding 1-101; catalytic 188-454 | + | *'''Pyrrolysyl-RS'''; domains – RNA-binding 1-101; catalytic 188-454 |
**[[2e3c]] - MmPylRS catalytic domain - ''Methanosarcina mazei''<br /> | **[[2e3c]] - MmPylRS catalytic domain - ''Methanosarcina mazei''<br /> | ||
| Line 619: | Line 617: | ||
**[[2zin]] - MmPylRS catalytic domain + butoxycarbonyl lysine + ATP analog <br /> | **[[2zin]] - MmPylRS catalytic domain + butoxycarbonyl lysine + ATP analog <br /> | ||
| - | *Ser-RS | + | *'''Ser-RS''' |
**[[3vbb]] - hSerRS <br /> | **[[3vbb]] - hSerRS <br /> | ||
| Line 650: | Line 648: | ||
**[[1ser]] – TtSerRS + Ser-tRNA<br /> | **[[1ser]] – TtSerRS + Ser-tRNA<br /> | ||
| - | *PhosphoSer-RS | + | *'''PhosphoSer-RS''' |
**[[2du4]] - AfPSerRS + Cys-tRNA<br /> | **[[2du4]] - AfPSerRS + Cys-tRNA<br /> | ||
| Line 656: | Line 654: | ||
**[[2du5]], [[2du6]] - AfPSerRS (mutant) + Cys-tRNA + phosphoserine<br /> | **[[2du5]], [[2du6]] - AfPSerRS (mutant) + Cys-tRNA + phosphoserine<br /> | ||
| - | *Thr-RS | + | *'''Thr-RS''' |
**[[1wwt]] – hThrRS TGS domain – NMR<br /> | **[[1wwt]] – hThrRS TGS domain – NMR<br /> | ||
| Line 693: | Line 691: | ||
**[[1kog]] – EcThrRS catalytic and anticodon-binding domains + mRNA<br /> | **[[1kog]] – EcThrRS catalytic and anticodon-binding domains + mRNA<br /> | ||
| - | *Multifunctional RS | + | *'''Multifunctional RS''' |
**[[1fyj]] – hRS – NMR<br /> | **[[1fyj]] – hRS – NMR<br /> | ||
}} | }} | ||
Revision as of 08:53, 12 March 2019
3D Structures of Aminoacyl tRNA synthetase
Updated on 12-March-2019
