6gxy

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Current revision (06:22, 1 October 2025) (edit) (undo)
 
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<StructureSection load='6gxy' size='340' side='right'caption='[[6gxy]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='6gxy' size='340' side='right'caption='[[6gxy]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6gxy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Trybb Trybb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GXY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GXY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6gxy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6GXY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FFN:5-(4-fluorophenyl)-2-methyl-3~{H}-thieno[2,3-d]pyrimidin-4-one'>FFN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6gxg|6gxg]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FFN:5-(4-fluorophenyl)-2-methyl-3~{H}-thieno[2,3-d]pyrimidin-4-one'>FFN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gxy OCA], [http://pdbe.org/6gxy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gxy RCSB], [http://www.ebi.ac.uk/pdbsum/6gxy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gxy ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6gxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gxy OCA], [https://pdbe.org/6gxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6gxy RCSB], [https://www.ebi.ac.uk/pdbsum/6gxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6gxy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TYPX_TRYBB TYPX_TRYBB]] Acts as a thiol-disulfide oxidoreductase. It is spontaneously reduced by trypanothione.
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[https://www.uniprot.org/uniprot/TYPX_TRYBB TYPX_TRYBB] Acts as a thiol-disulfide oxidoreductase. It is spontaneously reduced by trypanothione.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Trybb]]
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[[Category: Trypanosoma brucei brucei]]
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[[Category: Bader, N]]
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[[Category: Bader N]]
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[[Category: Hellmich, U]]
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[[Category: Hellmich U]]
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[[Category: Schindelin, H]]
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[[Category: Schindelin H]]
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[[Category: Wagner, A]]
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[[Category: Wagner A]]
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[[Category: Covalent inhibitor]]
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[[Category: Inhibitor-induced dimerization]]
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[[Category: Monomer-dimer mixture]]
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[[Category: Oxidoreductase]]
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[[Category: Photoreduction]]
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Current revision

Tryparedoxin from Trypanosoma brucei in complex with CFT

PDB ID 6gxy

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