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4bhp
From Proteopedia
(Difference between revisions)
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<StructureSection load='4bhp' size='340' side='right'caption='[[4bhp]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='4bhp' size='340' side='right'caption='[[4bhp]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4bhp]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4bhp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BHP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BHP FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bh9|4bh9]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4bh9|4bh9]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bhp OCA], [https://pdbe.org/4bhp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bhp RCSB], [https://www.ebi.ac.uk/pdbsum/4bhp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bhp ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CRP_ECOLI CRP_ECOLI]] This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons. The protein induces a severe bend in the DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP.<ref>PMID:2982847</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
| - | *[[Catabolite gene activator protein|Catabolite gene activator protein]] | + | *[[Catabolite gene activator protein 3D structures|Catabolite gene activator protein 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 07:14, 31 August 2022
A structural model of CAP mutant (T127L and S128I) in cGMP-bound state
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