4bq7
From Proteopedia
(Difference between revisions)
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<StructureSection load='4bq7' size='340' side='right'caption='[[4bq7]], [[Resolution|resolution]] 6.60Å' scene=''> | <StructureSection load='4bq7' size='340' side='right'caption='[[4bq7]], [[Resolution|resolution]] 6.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4bq7]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4bq7]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human] and [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BQ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BQ7 FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bq6|4bq6]], [[4bq8|4bq8]], [[4bq9|4bq9]], [[4bqb|4bqb]], [[4bqc|4bqc]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4bq6|4bq6]], [[4bq8|4bq8]], [[4bq9|4bq9]], [[4bqb|4bqb]], [[4bqc|4bqc]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bq7 OCA], [https://pdbe.org/4bq7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bq7 RCSB], [https://www.ebi.ac.uk/pdbsum/4bq7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bq7 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/NEO1_MOUSE NEO1_MOUSE]] May be involved as a regulatory protein in the transition of undifferentiated proliferating cells to their differentiated state. May also function as a cell adhesion molecule in a broad spectrum of embryonic and adult tissues. [[https://www.uniprot.org/uniprot/RGMB_HUMAN RGMB_HUMAN]] Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 07:21, 31 August 2022
Crystal structure of the RGMB-Neo1 complex form 2
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