Androgen receptor
From Proteopedia
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</StructureSection> | </StructureSection> | ||
| - | == 3D Structures of androgen receptor == | ||
| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *AR DBD domain | ||
| - | |||
| - | **[[1r4i]] – rAR (mutant) + DNA – rat<br /> | ||
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| - | *AR LBD domain | ||
| - | |||
| - | *''AR LBD domain complex with testosterone or DHT'' | ||
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| - | **[[1i37]] – rAR + DHT <br /> | ||
| - | **[[1i38]] – rAR (mutant) + DHT <br /> | ||
| - | **[[2ama]], [[4oea]] – hAR + DHT - human<br /> | ||
| - | **[[1t7t]] – cAR + DHT - chimpanzee<br /> | ||
| - | **[[2ylo]], [[2ylp]], [[2ylq]], [[3zqt]], [[4hlw]] – hAR + testosterone + benzoate derivative<br /> | ||
| - | **[[2pio]], [[2pip]], [[2piq]], [[2pir]], [[2pit]], [[2piu]], [[2piv]], [[2piw]], [[2pix]], [[2pkl]], [[2qpy]] – hAR + DHT + small molecule<br /> | ||
| - | **[[2yhd]] – hAR + testosterone + small molecule<br /> | ||
| - | **[[2am9]] – rAR + testosterone <br /> | ||
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| - | *''Other AR LBD domain complexes'' | ||
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| - | **[[1e3g]], [[1xq3]] – hAR + androgen <br /> | ||
| - | **[[1gs4]] – hAR (mutant) + corticosteroid<br /> | ||
| - | **[[1z95]], [[3rlj]] – hAR + anti-androgen <br /> | ||
| - | **[[2oz7]], [[3rll]], [[4ogh]], [[4ojb]] – hAR (mutant) + anti-androgen <br /> | ||
| - | **[[2ax6]], [[2ax7]], [[2ax8]] – hAR (mutant) + nonsteroidal ligand <br /> | ||
| - | **[[2ax9]], [[2axa]], [[4ql8]] – hAR + nonsteroidal ligand <br /> | ||
| - | **[[2amb]], [[2pnu]] – hAR + steroid <br /> | ||
| - | **[[1xnn]] – rAR (mutant) + nonsteroidal ligand <br /> | ||
| - | **[[2ihq]], [[2nw4]], [[3g0w]] – rAR + modulator <br /> | ||
| - | **[[2hvc]], [[3b5r]], [[3b65]], [[3b66]], [[3b67]], [[3b68]], [[5vo4]], [[5v8q]], [[5t8e]], [[5t8j]] – hAR + modulator <br /> | ||
| - | **[[4k7a]] – hAR + hair growth drug <br /> | ||
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| - | *''AR LBD domain complex with peptide'' | ||
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| - | **[[1t73]], [[1t74]], [[1t76]], [[1t79]], [[1t7f]], [[1t7m]], [[1t7r]] – cAR + FXXFF-type peptide <br /> | ||
| - | **[[1xow]] – hAR + androgen + FXXFF-type peptide <br /> | ||
| - | **[[3v49]], [[3v4a]] – hAR + modulator + FXXFF-type peptide <br /> | ||
| - | **[[5jjm]] – hAR + DHT + LXXLL peptide <br /> | ||
| - | **[[5cj6]] – hAR + modulator peptide <br /> | ||
| - | **[[1t5z]] – hAR + DHT + nuclear receptor coactivator 1 peptide<br /> | ||
| - | **[[1t63]], [[1t65]] – hAR + DHT + nuclear receptor coactivator 2 peptide<br /> | ||
| - | **[[3l3x]], [[3l3z]] – hAR + DHT + nuclear receptor coactivator 3 peptide<br /> | ||
| - | **[[4oed]], [[4oey]], [[4oez]], [[4ofr]], [[4ofu]] – hAR (mutant) + DHT + co-regulator peptide <br /> | ||
| - | **[[4oh5]], [[4oh6]], [[4oha]], [[4oil]], [[4oiu]], [[4oj9]], [[4ok1]], [[4okb]], [[4okt]], [[4okw]], [[4okx]], [[4olm]] – hAR (mutant) + antiandrogen + co-regulator peptide <br /> | ||
| - | **[[2z4j]] – hAR + DHT + nuclear receptor 0B2 peptide<br /> | ||
| - | **[[2q7j]] – hAR + testosterone + nuclear receptor coactivator 2 peptide<br /> | ||
| - | **[[2q7k]], [[2q7l]] – hAR (mutant) + testosterone + nuclear receptor coactivator 2 peptide<br /> | ||
| - | **[[2ao6]] – hAR + nuclear receptor coactivator 2 peptide<br /> | ||
| - | **[[1xj7]] – hAR + DHT + RAC3 peptide<br /> | ||
| - | }} | ||
==See Also== | ==See Also== | ||
* [[Hormone]] | * [[Hormone]] | ||
Revision as of 08:20, 17 March 2019
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See Also
References
- ↑ Bohl CE, Wu Z, Chen J, Mohler ML, Yang J, Hwang DJ, Mustafa S, Miller DD, Bell CE, Dalton JT. Effect of B-ring substitution pattern on binding mode of propionamide selective androgen receptor modulators. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5567-70. Epub 2008 Sep 5. PMID:18805694 doi:10.1016/j.bmcl.2008.09.002
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Cristina Benito, Michal Harel, Cristina Murga, Marta Roldan Lazaro, Alexander Berchansky, Joel L. Sussman, Wayne Decatur, David Sánchez Fernández
