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6qy1
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Pink beam serial crystallography: Lysozyme, 5 us exposure, 1500 patterns merged== | |
| + | <StructureSection load='6qy1' size='340' side='right'caption='[[6qy1]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6qy1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QY1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QY1 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6qxv|6qxv]], [[6qxw|6qxw]], [[6qxx|6qxx]], [[6qxy|6qxy]], [[6qy0|6qy0]]</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qy1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qy1 OCA], [http://pdbe.org/6qy1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qy1 RCSB], [http://www.ebi.ac.uk/pdbsum/6qy1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qy1 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Reliable sample delivery and efficient use of limited beam time have remained bottlenecks for serial crystallography (SX). Using a high-intensity polychromatic X-ray beam in combination with a newly developed charge-integrating JUNGFRAU detector, we have applied the method of fixed-target SX to collect data at a rate of 1 kHz at a synchrotron-radiation facility. According to our data analysis for the given experimental conditions, only about 3 000 diffraction patterns are required for a high-quality diffraction dataset. With indexing rates of up to 25%, recording of such a dataset takes less than 30 s. | ||
| - | + | 1 kHz fixed-target serial crystallography using a multilayer monochromator and an integrating pixel detector.,Tolstikova A, Levantino M, Yefanov O, Hennicke V, Fischer P, Meyer J, Mozzanica A, Redford S, Crosas E, Opara NL, Barthelmess M, Lieske J, Oberthuer D, Wator E, Mohacsi I, Wulff M, Schmitt B, Chapman HN, Meents A IUCrJ. 2019 Aug 17;6(Pt 5):927-937. doi: 10.1107/S205225251900914X. eCollection, 2019 Sep 1. PMID:31576225<ref>PMID:31576225</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 6qy1" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Gallus gallus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lysozyme]] | ||
[[Category: Lieske, J]] | [[Category: Lieske, J]] | ||
| - | [[Category: Tolstikova, A]] | ||
[[Category: Meents, A]] | [[Category: Meents, A]] | ||
| + | [[Category: Tolstikova, A]] | ||
| + | [[Category: Fixed-target]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Pink beam]] | ||
| + | [[Category: Serial crystallography]] | ||
Revision as of 06:22, 10 October 2019
Pink beam serial crystallography: Lysozyme, 5 us exposure, 1500 patterns merged
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