2n87
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2n87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n87 OCA], [http://pdbe.org/2n87 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2n87 RCSB], [http://www.ebi.ac.uk/pdbsum/2n87 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2n87 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2n87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n87 OCA], [http://pdbe.org/2n87 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2n87 RCSB], [http://www.ebi.ac.uk/pdbsum/2n87 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2n87 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Trypanosoma brucei is a unicellular eukaryotic parasite, which causes the African sleeping sickness in humans. The recently discovered trypanosomal protein Parvulin 42 (TbPar42) plays a key role in parasite cell proliferation. Homologues of this two-domain protein are exclusively found in protozoa species. TbPar42 exhibits an N-terminal forkhead associated (FHA)-domain and a peptidyl-prolyl-cis/trans-isomerase (PPIase) domain, both connected by a linker. Using NMR and X-ray analysis as well as activity assays, we report on the structures of the single domains of TbPar42, discuss their intra-molecular interplay, and give some initial hints as to potential cellular functions of the protein. | ||
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| + | Structural Analysis of the 42 kDa Parvulin of Trypanosoma brucei.,Rehic E, Hoenig D, Kamba BE, Goehring A, Hofmann E, Gasper R, Matena A, Bayer P Biomolecules. 2019 Mar 7;9(3). pii: biom9030093. doi: 10.3390/biom9030093. PMID:30866577<ref>PMID:30866577</ref> | ||
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| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 2n87" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 15:49, 20 November 2019
Solution structure of the PPIase domain of TbPar42
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Categories: Large Structures | Tryb2 | Bayer, P | Rehic, E | Isomerase | Parvulin | Ppiase domain
