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6qo3
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with Fragment 2 (5-Amino-3-(2-thienyl) pyrazole)== | |
| - | + | <StructureSection load='6qo3' size='340' side='right'caption='[[6qo3]], [[Resolution|resolution]] 1.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6qo3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QO3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QO3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=J9N:5-thiophen-2-yl-4~{H}-pyrazol-3-amine'>J9N</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6nvr|6nvr]]</td></tr> |
| - | [[Category: Blundell, T | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qo3 OCA], [http://pdbe.org/6qo3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qo3 RCSB], [http://www.ebi.ac.uk/pdbsum/6qo3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qo3 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/B1MDI3_MYCA9 B1MDI3_MYCA9]] Specifically methylates guanosine-37 in various tRNAs.[HAMAP-Rule:MF_00605][RuleBase:RU003464][SAAS:SAAS00040552] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Abell, C]] | ||
| + | [[Category: Blundell, T L]] | ||
| + | [[Category: Coyne, A G]] | ||
[[Category: Mendes, V]] | [[Category: Mendes, V]] | ||
| - | [[Category: Thomas, S | + | [[Category: Thomas, S E]] |
| - | [[Category: | + | [[Category: Whitehouse, A J]] |
| - | [[Category: | + | [[Category: Spout methyltransferase]] |
| - | [[Category: | + | [[Category: Transferase]] |
| + | [[Category: Trmd]] | ||
| + | [[Category: Trna methyltransferase]] | ||
Revision as of 06:46, 4 March 2020
Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with Fragment 2 (5-Amino-3-(2-thienyl) pyrazole)
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