5qgg
From Proteopedia
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<StructureSection load='5qgg' size='340' side='right'caption='[[5qgg]], [[Resolution|resolution]] 1.91Å' scene=''>  | <StructureSection load='5qgg' size='340' side='right'caption='[[5qgg]], [[Resolution|resolution]] 1.91Å' scene=''>  | ||
== Structural highlights ==  | == Structural highlights ==  | ||
| - | <table><tr><td colspan='2'>[[5qgg]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QGG OCA]. For a <b>guided tour on the structure components</b> use [  | + | <table><tr><td colspan='2'>[[5qgg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QGG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QGG FirstGlance]. <br>  | 
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=H2G:(2S)-1-{[(5-methylthiophen-2-yl)methyl]amino}propan-2-ol'>H2G  | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.91Å</td></tr>  | 
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=H2G:(2S)-1-{[(5-methylthiophen-2-yl)methyl]amino}propan-2-ol'>H2G</scene>, <scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>  | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[  | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qgg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qgg OCA], [https://pdbe.org/5qgg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qgg RCSB], [https://www.ebi.ac.uk/pdbsum/5qgg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qgg ProSAT]</span></td></tr>  | 
</table>  | </table>  | ||
== Function ==  | == Function ==  | ||
| - | [  | + | [https://www.uniprot.org/uniprot/NUDT7_HUMAN NUDT7_HUMAN] Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products. CoA into 3',5'-ADP and 4'-phosphopantetheine. Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA (By similarity).  | 
__TOC__  | __TOC__  | ||
</StructureSection>  | </StructureSection>  | ||
| + | [[Category: Homo sapiens]]  | ||
[[Category: Large Structures]]  | [[Category: Large Structures]]  | ||
| - | [[Category: Aimon  | + | [[Category: Aimon A]]  | 
| - | [[Category: Arrowsmith  | + | [[Category: Arrowsmith CH]]  | 
| - | [[Category: Bountra  | + | [[Category: Bountra C]]  | 
| - | [[Category: Bradley  | + | [[Category: Bradley AR]]  | 
| - | [[Category: Brandao-Neto  | + | [[Category: Brandao-Neto J]]  | 
| - | [[Category: Brennan  | + | [[Category: Brennan PE]]  | 
| - | [[Category: Collins  | + | [[Category: Collins P]]  | 
| - | [[Category:   | + | [[Category: Diaz Saez L]]  | 
| - | [[Category: Douangamath  | + | [[Category: Douangamath A]]  | 
| - | [[Category: Edwards  | + | [[Category: Edwards A]]  | 
| - | [[Category: Elkins  | + | [[Category: Elkins J]]  | 
| - | [[Category: Fairhead  | + | [[Category: Fairhead M]]  | 
| - | [[Category: Huber  | + | [[Category: Huber K]]  | 
| - | [[Category: Krojer  | + | [[Category: Krojer T]]  | 
| - | [[Category: London  | + | [[Category: London N]]  | 
| - | [[Category: Nelson  | + | [[Category: Nelson A]]  | 
| - | [[Category: Ruda  | + | [[Category: Ruda GF]]  | 
| - | + | [[Category: Spencer J]]  | |
| - | [[Category: Spencer  | + | [[Category: Srikannathasan V]]  | 
| - | [[Category: Srikannathasan  | + | [[Category: Szommer T]]  | 
| - | [[Category: Szommer  | + | [[Category: Talon R]]  | 
| - | [[Category: Talon  | + | [[Category: Von Delft F]]  | 
| - | [[Category:   | + | |
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Current revision
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT7 in complex with FMOPL000693a
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Categories: Homo sapiens | Large Structures | Aimon A | Arrowsmith CH | Bountra C | Bradley AR | Brandao-Neto J | Brennan PE | Collins P | Diaz Saez L | Douangamath A | Edwards A | Elkins J | Fairhead M | Huber K | Krojer T | London N | Nelson A | Ruda GF | Spencer J | Srikannathasan V | Szommer T | Talon R | Von Delft F
