5qhg

<table><tr><td colspan='2'>[[5qhg]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QHG FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=H17:2-{3-[(2R)-1-acryloylpyrrolidin-2-yl]phenyl}-N-(3-chlorophenyl)acetamide'>H17</scene></td></tr>

<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qhg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qhg OCA], [http://pdbe.org/5qhg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qhg RCSB], [http://www.ebi.ac.uk/pdbsum/5qhg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qhg ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/NUDT7_HUMAN NUDT7_HUMAN]] Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products. CoA into 3',5'-ADP and 4'-phosphopantetheine. Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA (By similarity).

[[Category: Aimon, A]]

[[Category: Arrowsmith, C H]]

[[Category: Bountra, C]]

[[Category: Bradley, A R]]

[[Category: Brandao-Neto, J]]

[[Category: Brennan, P E]]

[[Category: Collins, P]]

[[Category: Delft, F von]]

[[Category: Douangamath, A]]

[[Category: Edwards, A]]

[[Category: Elkins, J]]

[[Category: Fairhead, M]]

[[Category: Huber, K]]

[[Category: Krojer, T]]

[[Category: London, N]]

[[Category: Nelson, A]]

[[Category: Ruda, G F]]

[[Category: Saez, L Diaz]]

[[Category: Spencer, J]]

[[Category: Srikannathasan, V]]

[[Category: Szommer, T]]

[[Category: Talon, R]]

[[Category: Hydrolase]]

[[Category: Xchemexplorer]]