6gmp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:34, 1 May 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='6gmp' size='340' side='right'caption='[[6gmp]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
<StructureSection load='6gmp' size='340' side='right'caption='[[6gmp]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6gmp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Tryb2 Tryb2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GMP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GMP FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[6gmp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_TREU927 Trypanosoma brucei brucei TREU927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GMP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6GMP FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2mnt|2mnt]], [[2n87|2n87]], [[2n84|2n84]]</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tb927.7.2480 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=185431 TRYB2])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6gmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gmp OCA], [https://pdbe.org/6gmp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6gmp RCSB], [https://www.ebi.ac.uk/pdbsum/6gmp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6gmp ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gmp OCA], [http://pdbe.org/6gmp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gmp RCSB], [http://www.ebi.ac.uk/pdbsum/6gmp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gmp ProSAT]</span></td></tr>
+
</table>
</table>
-
<div style="background-color:#fffaf0;">
+
== Function ==
-
== Publication Abstract from PubMed ==
+
[https://www.uniprot.org/uniprot/Q57XM6_TRYB2 Q57XM6_TRYB2]
-
Trypanosoma brucei is a unicellular eukaryotic parasite, which causes the African sleeping sickness in humans. The recently discovered trypanosomal protein Parvulin 42 (TbPar42) plays a key role in parasite cell proliferation. Homologues of this two-domain protein are exclusively found in protozoa species. TbPar42 exhibits an N-terminal forkhead associated (FHA)-domain and a peptidyl-prolyl-cis/trans-isomerase (PPIase) domain, both connected by a linker. Using NMR and X-ray analysis as well as activity assays, we report on the structures of the single domains of TbPar42, discuss their intra-molecular interplay, and give some initial hints as to potential cellular functions of the protein.
+
-
 
+
-
Structural Analysis of the 42 kDa Parvulin of Trypanosoma brucei.,Rehic E, Hoenig D, Kamba BE, Goehring A, Hofmann E, Gasper R, Matena A, Bayer P Biomolecules. 2019 Mar 7;9(3). pii: biom9030093. doi: 10.3390/biom9030093. PMID:30866577<ref>PMID:30866577</ref>
+
-
 
+
-
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+
-
</div>
+
-
<div class="pdbe-citations 6gmp" style="background-color:#fffaf0;"></div>
+
-
== References ==
+
-
<references/>
+
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Tryb2]]
+
[[Category: Trypanosoma brucei brucei TREU927]]
-
[[Category: Bayer, P]]
+
[[Category: Bayer P]]
-
[[Category: Gasper, R]]
+
[[Category: Gasper R]]
-
[[Category: Hoenig, D]]
+
[[Category: Hoenig D]]
-
[[Category: Hofmann, E]]
+
[[Category: Hofmann E]]
-
[[Category: Rute, A]]
+
[[Category: Rute A]]
-
[[Category: Isomerase]]
+
-
[[Category: Ppiase]]
+

Current revision

CRYSTAL STRUCTURE OF THE PPIASE DOMAIN OF TBPAR42

PDB ID 6gmp

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6gmp"
Personal tools