User:Sean Callahan/Sandbox 1

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== Function ==
== Function ==
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Although the hydrophobic pocket plays the major role in positioning the FAD cofactor and lysine substrate, <scene name='81/811711/Lysine_661/3'>Lysine 661</scene> is a crucial, positively charged residue that is responsible for stabilizing FAD by creating a H-bond with
===SWIRM Domain===
===SWIRM Domain===
The <scene name='81/811711/Swirm_domain/2'>SWIRM domain</scene>
The <scene name='81/811711/Swirm_domain/2'>SWIRM domain</scene>

Revision as of 18:23, 29 March 2019

=Lysine Specific Demethylase 1 (Homo sapiens)=

LSD1 2h94

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References

[3] [4]

  1. Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
  3. Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
  4. Mineo R, Sharrock NE. Venous levels of lidocaine and bupivacaine after midtarsal ankle block. Reg Anesth. 1992 Jan-Feb;17(1):47-9. PMID:1599895

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Sean Callahan

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