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Gelsolin
From Proteopedia
(Difference between revisions)
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GLS contains 6 homologous domains S1 to S6. The human GLS domains span residues: 15-135, 136-248, 249-367, 394-513, 514-619 and 620-734. <scene name='41/410297/Cv/6'>S4-S6 are shown</scene>. The <scene name='41/410297/Cv/7'>binding site of Ca+2 ion includes Glu, Asp and 2 carbonyl oxygens</scene><ref>PMID:12460571</ref>. | GLS contains 6 homologous domains S1 to S6. The human GLS domains span residues: 15-135, 136-248, 249-367, 394-513, 514-619 and 620-734. <scene name='41/410297/Cv/6'>S4-S6 are shown</scene>. The <scene name='41/410297/Cv/7'>binding site of Ca+2 ion includes Glu, Asp and 2 carbonyl oxygens</scene><ref>PMID:12460571</ref>. | ||
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| + | == 3D Structures of gelsolin == | ||
| + | [[3D Structures of gelsolin]] | ||
| + | |||
</StructureSection> | </StructureSection> | ||
| - | == 3D Structures of | + | == 3D Structures of gelsolin == |
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
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**[[3ffn]] – hGLS – human <br /> | **[[3ffn]] – hGLS – human <br /> | ||
| + | **[[6jeg]], [[6jeh]], [[6jco]] - hGLS (mutant) <br /> | ||
**[[2fgh]] – hoGLS+ATP – horse <br /> | **[[2fgh]] – hoGLS+ATP – horse <br /> | ||
**[[1d0n]] - hoGLS <br /> | **[[1d0n]] - hoGLS <br /> | ||
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* GLS domain S1 residues 51-178 | * GLS domain S1 residues 51-178 | ||
| + | **[[5zz0]] – hGLS <br /> | ||
**[[5h3m]], [[5h3n]] – hGLS – NMR<br /> | **[[5h3m]], [[5h3n]] – hGLS – NMR<br /> | ||
**[[2ff3]] - hGLS +N-WASP+actin<br /> | **[[2ff3]] - hGLS +N-WASP+actin<br /> | ||
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**[[3cjb]] - rGLS +rActin<br /> | **[[3cjb]] - rGLS +rActin<br /> | ||
**[[3cjc]] - rGLS +rActin+DNAse I<br /> | **[[3cjc]] - rGLS +rActin+DNAse I<br /> | ||
| - | **[[4cbu]], [[4cbw]], [[4cbx]], [[5mvv]] - mGLS +actin+ | + | **[[4cbu]], [[4cbw]], [[4cbx]], [[5mvv]], [[6i4d]], [[6i4e]], [[6i4f]], [[6i4g]], [[6i4h]], [[6i4i]], [[6i4j]], [[6i4k]], [[6i4l]], [[6i4m]] - mGLS +actin+ nucleotide<br /> |
*GLS S2 residues 178-293 | *GLS S2 residues 178-293 | ||
**[[5fae]], [[5faf]], [[5o2z]] - hGLS (mutant) <br /> | **[[5fae]], [[5faf]], [[5o2z]] - hGLS (mutant) <br /> | ||
| - | **[[4s10]] - hGLS (mutant) + antibody<br /> | + | **[[4s10]], [[6h1f]] - hGLS (mutant) + antibody<br /> |
* GLS domains S1-S3 residues 52-426 | * GLS domains S1-S3 residues 52-426 | ||
Revision as of 09:08, 9 July 2019
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3D Structures of gelsolin
Updated on 09-July-2019
References
- ↑ Sun HQ, Yamamoto M, Mejillano M, Yin HL. Gelsolin, a multifunctional actin regulatory protein. J Biol Chem. 1999 Nov 19;274(47):33179-82. PMID:10559185
- ↑ Choe H, Burtnick LD, Mejillano M, Yin HL, Robinson RC, Choe S. The calcium activation of gelsolin: insights from the 3A structure of the G4-G6/actin complex. J Mol Biol. 2002 Dec 6;324(4):691-702. PMID:12460571
