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2wg2
From Proteopedia
(Difference between revisions)
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<StructureSection load='2wg2' size='340' side='right'caption='[[2wg2]], [[Resolution|resolution]] 1.95Å' scene=''> | <StructureSection load='2wg2' size='340' side='right'caption='[[2wg2]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2wg2]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2wg2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WG2 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GD8:(1R)-1,2,2-TRIMETHYLPROPYL+(S)-METHYLPHOSPHINATE'>GD8</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zgb|1zgb]], [[1amn|1amn]], [[1qti|1qti]], [[1e66|1e66]], [[2j3d|2j3d]], [[2vq6|2vq6]], [[2ack|2ack]], [[1qii|1qii]], [[2ckm|2ckm]], [[1dx6|1dx6]], [[1qie|1qie]], [[1qij|1qij]], [[1acl|1acl]], [[1odc|1odc]], [[1w4l|1w4l]], [[2cmf|2cmf]], [[1gqs|1gqs]], [[2j3q|2j3q]], [[2j4f|2j4f]], [[1e3q|1e3q]], [[1qik|1qik]], [[2dfp|2dfp]], [[2c5f|2c5f]], [[1ea5|1ea5]], [[1eea|1eea]], [[1qif|1qif]], [[2vjc|2vjc]], [[2vjb|2vjb]], [[1qig|1qig]], [[1zgc|1zgc]], [[1qid|1qid]], [[1jjb|1jjb]], [[2vjd|2vjd]], [[1ut6|1ut6]], [[2vt6|2vt6]], [[2w9i|2w9i]], [[2vt7|2vt7]], [[2cek|2cek]], [[1qim|1qim]], [[1jga|1jga]], [[1gpk|1gpk]], [[3ace|3ace]], [[1oce|1oce]], [[1w6r|1w6r]], [[1som|1som]], [[1vxo|1vxo]], [[2vja|2vja]], [[2w6c|2w6c]], [[1cfj|1cfj]], [[2v96|2v96]], [[1ax9|1ax9]], [[1u65|1u65]], [[1w76|1w76]], [[1h22|1h22]], [[1eve|1eve]], [[2c4h|2c4h]], [[1gqr|1gqr]], [[2ace|2ace]], [[2va9|2va9]], [[1vxr|1vxr]], [[4ace|4ace]], [[2c58|2c58]], [[1hbj|1hbj]], [[1w75|1w75]], [[1vot|1vot]], [[2c5g|2c5g]], [[2v98|2v98]], [[1jgb|1jgb]], [[1gpn|1gpn]], [[1qih|1qih]], [[1h23|1h23]], [[1fss|1fss]], [[1acj|1acj]], [[2v97|2v97]], [[2wg1|2wg1]], [[2wg0|2wg0]], [[2wfz|2wfz]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1zgb|1zgb]], [[1amn|1amn]], [[1qti|1qti]], [[1e66|1e66]], [[2j3d|2j3d]], [[2vq6|2vq6]], [[2ack|2ack]], [[1qii|1qii]], [[2ckm|2ckm]], [[1dx6|1dx6]], [[1qie|1qie]], [[1qij|1qij]], [[1acl|1acl]], [[1odc|1odc]], [[1w4l|1w4l]], [[2cmf|2cmf]], [[1gqs|1gqs]], [[2j3q|2j3q]], [[2j4f|2j4f]], [[1e3q|1e3q]], [[1qik|1qik]], [[2dfp|2dfp]], [[2c5f|2c5f]], [[1ea5|1ea5]], [[1eea|1eea]], [[1qif|1qif]], [[2vjc|2vjc]], [[2vjb|2vjb]], [[1qig|1qig]], [[1zgc|1zgc]], [[1qid|1qid]], [[1jjb|1jjb]], [[2vjd|2vjd]], [[1ut6|1ut6]], [[2vt6|2vt6]], [[2w9i|2w9i]], [[2vt7|2vt7]], [[2cek|2cek]], [[1qim|1qim]], [[1jga|1jga]], [[1gpk|1gpk]], [[3ace|3ace]], [[1oce|1oce]], [[1w6r|1w6r]], [[1som|1som]], [[1vxo|1vxo]], [[2vja|2vja]], [[2w6c|2w6c]], [[1cfj|1cfj]], [[2v96|2v96]], [[1ax9|1ax9]], [[1u65|1u65]], [[1w76|1w76]], [[1h22|1h22]], [[1eve|1eve]], [[2c4h|2c4h]], [[1gqr|1gqr]], [[2ace|2ace]], [[2va9|2va9]], [[1vxr|1vxr]], [[4ace|4ace]], [[2c58|2c58]], [[1hbj|1hbj]], [[1w75|1w75]], [[1vot|1vot]], [[2c5g|2c5g]], [[2v98|2v98]], [[1jgb|1jgb]], [[1gpn|1gpn]], [[1qih|1qih]], [[1h23|1h23]], [[1fss|1fss]], [[1acj|1acj]], [[2v97|2v97]], [[2wg1|2wg1]], [[2wg0|2wg0]], [[2wfz|2wfz]]</div></td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wg2 OCA], [https://pdbe.org/2wg2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wg2 RCSB], [https://www.ebi.ac.uk/pdbsum/2wg2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wg2 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ACES_TORCA ACES_TORCA]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 09:25, 12 May 2021
NON-AGED CONJUGATE OF TORPEDO CALIFORNICA ACETYLCHOLINESTERASE WITH SOMAN (ALTERNATIVE REFINEMENT)
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Categories: Acetylcholinesterase | Large Structures | Torpedo californica | Ashani, Y | Colletier, J P | Froment, M T | Greenblatt, H M | Masson, P | Nachon, F | Sanson, B | Silman, I | Sussman, J L | Toker, L | Weik, M | Aging | Alzheimer disease | Cell junction | Cell membrane | Glycoprotein | Gpi-anchor | Hydrolase | Neurotransmitter degradation | Synapse membrane

