SCP2-thiolase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 15: Line 15:
== Function ==
== Function ==
-
Here '''something''' about ''function'' <ref>pmid 25203508</ref>
+
Here '''something''' about ''function'' <ref>pmid 16685654</ref>
== Disease ==
== Disease ==
Line 22: Line 22:
== Structural highlights ==
== Structural highlights ==
-
When the A and B monomers are compared the structural differences can best be seen in this <scene name='80/809821/Morph/7'>morph</scene>.
+
When the A and B monomers are compared the structural differences can best be seen in this <scene name='80/809821/Morph/8'>morph</scene>.

Revision as of 13:57, 8 April 2019

Structure of the zebrafish SCP2-thiolase [1]

This is the asymmetric unit. Resolution 1.7Å.

Drag the structure with the mouse to rotate

References

  1. Kiema TR, Thapa CJ, Laitaoja M, Schmitz W, Maksimainen MM, Fukao T, Rouvinen J, Janis J, Wierenga RK. The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry. Biochem J. 2018 Dec 20. pii: BCJ20180788. doi: 10.1042/BCJ20180788. PMID:30573650 doi:http://dx.doi.org/10.1042/BCJ20180788
  2. Anbazhagan P, Harijan RK, Kiema TR, Janardan N, Murthy MR, Michels PA, Juffer AH, Wierenga RK. Phylogenetic relationships and classification of thiolases and thiolase-like proteins of Mycobacterium tuberculosis and Mycobacterium smegmatis. Tuberculosis (Edinb). 2014 Jul;94(4):405-12. doi: 10.1016/j.tube.2014.03.003., Epub 2014 Apr 4. PMID:24825023 doi:http://dx.doi.org/10.1016/j.tube.2014.03.003
  3. Ferdinandusse S, Kostopoulos P, Denis S, Rusch H, Overmars H, Dillmann U, Reith W, Haas D, Wanders RJ, Duran M, Marziniak M. Mutations in the gene encoding peroxisomal sterol carrier protein X (SCPx) cause leukencephalopathy with dystonia and motor neuropathy. Am J Hum Genet. 2006 Jun;78(6):1046-52. Epub 2006 Mar 29. PMID:16685654 doi:10.1086/503921

Proteopedia Page Contributors and Editors (what is this?)

Rik Wierenga, Michal Harel

Personal tools