6a6k

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Current revision (09:19, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6a6k' size='340' side='right'caption='[[6a6k]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='6a6k' size='340' side='right'caption='[[6a6k]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6a6k]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A6K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6A6K FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6a6k]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A6K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6A6K FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9S6:3-[(~{E})-5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol'>9S6</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6a6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a6k OCA], [http://pdbe.org/6a6k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6a6k RCSB], [http://www.ebi.ac.uk/pdbsum/6a6k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6a6k ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9S6:3-[(~{E})-5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol'>9S6</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6a6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a6k OCA], [https://pdbe.org/6a6k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6a6k RCSB], [https://www.ebi.ac.uk/pdbsum/6a6k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6a6k ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ERR3_HUMAN ERR3_HUMAN]] Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity).<ref>PMID:19067653</ref> <ref>PMID:18063693</ref> <ref>PMID:11864604</ref>
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[https://www.uniprot.org/uniprot/ERR3_HUMAN ERR3_HUMAN] Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity).<ref>PMID:19067653</ref> <ref>PMID:18063693</ref> <ref>PMID:11864604</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6a6k" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6a6k" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Estrogen-related receptor 3D structures|Estrogen-related receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chin, J]]
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[[Category: Chin J]]
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[[Category: Cho, S J]]
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[[Category: Cho SJ]]
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[[Category: Kim, J]]
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[[Category: Kim J]]
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[[Category: Song, J]]
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[[Category: Song J]]
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[[Category: Yoon, H]]
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[[Category: Yoon H]]
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[[Category: Anaplastic thyroid cancer]]
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[[Category: Estrogen-related receptor gamma]]
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[[Category: Radioiodine therapy]]
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[[Category: Transcription]]
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Current revision

Crystal structure of Estrogen-related Receptor-3 (ERR-gamma) ligand binding domain with DN201000

PDB ID 6a6k

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