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4n1s

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<StructureSection load='4n1s' size='340' side='right'caption='[[4n1s]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
<StructureSection load='4n1s' size='340' side='right'caption='[[4n1s]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4n1s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N1S FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4n1s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N1S FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=WM4:BENZOHYDRAZIDE'>WM4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=WM4:BENZOHYDRAZIDE'>WM4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4n1m|4n1m]], [[4n1n|4n1n]], [[4n1o|4n1o]], [[4n1p|4n1p]], [[4n1q|4n1q]], [[4n1r|4n1r]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1s OCA], [https://pdbe.org/4n1s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n1s RCSB], [https://www.ebi.ac.uk/pdbsum/4n1s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n1s ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPIA, CYPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1s OCA], [http://pdbe.org/4n1s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4n1s RCSB], [http://www.ebi.ac.uk/pdbsum/4n1s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4n1s ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PPIA_HUMAN PPIA_HUMAN]] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
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[https://www.uniprot.org/uniprot/PPIA_HUMAN PPIA_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
==See Also==
==See Also==
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*[[Cyclophilin|Cyclophilin]]
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*[[Cyclophilin 3D structures|Cyclophilin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Peptidylprolyl isomerase]]
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[[Category: Dornan J]]
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[[Category: Dornan, J]]
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[[Category: Mcnae IW]]
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[[Category: Mcnae, I W]]
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[[Category: Walkinshaw MD]]
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[[Category: Walkinshaw, M D]]
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[[Category: Beta barrel]]
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[[Category: Cytosolic]]
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[[Category: Isomerase]]
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[[Category: Ligand complex]]
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[[Category: Prolyl cis/trans isomerase]]
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Revision as of 10:27, 28 December 2022

Structure of Cyclophilin A in complex with benzohydrazide.

PDB ID 4n1s

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