This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4mji

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:41, 28 December 2022) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='4mji' size='340' side='right'caption='[[4mji]], [[Resolution|resolution]] 2.99&Aring;' scene=''>
<StructureSection load='4mji' size='340' side='right'caption='[[4mji]], [[Resolution|resolution]] 2.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4mji]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MJI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MJI FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4mji]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MJI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MJI FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HLA-B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), B2M ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mji OCA], [https://pdbe.org/4mji PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mji RCSB], [https://www.ebi.ac.uk/pdbsum/4mji PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mji ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mji OCA], [http://pdbe.org/4mji PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mji RCSB], [http://www.ebi.ac.uk/pdbsum/4mji PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mji ProSAT]</span></td></tr>
+
</table>
</table>
-
== Disease ==
 
-
[[http://www.uniprot.org/uniprot/B2MG_HUMAN B2MG_HUMAN]] Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP) [MIM:[http://omim.org/entry/241600 241600]]. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.<ref>PMID:16549777</ref> Note=Beta-2-microglobulin may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. Persistently high beta(2)-microglobulin serum levels lead to amyloidosis in patients on long-term hemodialysis.<ref>PMID:3532124</ref> <ref>PMID:1336137</ref> <ref>PMID:7554280</ref> <ref>PMID:4586824</ref> <ref>PMID:8084451</ref> <ref>PMID:12119416</ref> <ref>PMID:12796775</ref> <ref>PMID:16901902</ref> <ref>PMID:16491088</ref> <ref>PMID:17646174</ref> <ref>PMID:18835253</ref> <ref>PMID:18395224</ref> <ref>PMID:19284997</ref>
 
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/1B51_HUMAN 1B51_HUMAN]] Involved in the presentation of foreign antigens to the immune system. [[http://www.uniprot.org/uniprot/B2MG_HUMAN B2MG_HUMAN]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
+
[https://www.uniprot.org/uniprot/R4WL38_9HIV1 R4WL38_9HIV1]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 20:
==See Also==
==See Also==
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
-
*[[T-cell receptor|T-cell receptor]]
+
*[[T-cell receptor 3D structures|T-cell receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
 +
[[Category: Human immunodeficiency virus 1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Cole, D K]]
+
[[Category: Cole DK]]
-
[[Category: Motozono, C]]
+
[[Category: Motozono C]]
-
[[Category: Rizkallah, P J]]
+
[[Category: Rizkallah PJ]]
-
[[Category: Sewell, A K]]
+
[[Category: Sewell AK]]
-
[[Category: Takiguchi, M]]
+
[[Category: Takiguchi M]]
-
[[Category: Antigen presentation]]
+
-
[[Category: Class i mhc]]
+
-
[[Category: Hiv]]
+
-
[[Category: Immune system]]
+
-
[[Category: Immunoglobulin]]
+
-
[[Category: Peptide-major histocompatibility complex]]
+
-
[[Category: Pmhc]]
+
-
[[Category: Spr]]
+
-
[[Category: Surface plasmon resonance]]
+
-
[[Category: T-cell]]
+
-
[[Category: T-cell receptor]]
+
-
[[Category: Tcr]]
+

Current revision

T cell response to a HIV reverse transcriptase epitope presented by the protective allele HLA-B*51:01

PDB ID 4mji

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4mji"
Personal tools