This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4mqu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='4mqu' size='340' side='right'caption='[[4mqu]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
<StructureSection load='4mqu' size='340' side='right'caption='[[4mqu]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4mqu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MQU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MQU FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4mqu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MQU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MQU FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MG9:2-{4-[(2S)-4-[(6-AMINOPYRIDIN-3-YL)SULFONYL]-2-(PROP-1-YN-1-YL)PIPERAZIN-1-YL]PHENYL}-1,1,1,3,3,3-HEXAFLUOROPROPAN-2-OL'>MG9</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MG9:2-{4-[(2S)-4-[(6-AMINOPYRIDIN-3-YL)SULFONYL]-2-(PROP-1-YN-1-YL)PIPERAZIN-1-YL]PHENYL}-1,1,1,3,3,3-HEXAFLUOROPROPAN-2-OL'>MG9</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mro|4mro]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mqu OCA], [https://pdbe.org/4mqu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mqu RCSB], [https://www.ebi.ac.uk/pdbsum/4mqu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mqu ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GCKR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mqu OCA], [http://pdbe.org/4mqu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mqu RCSB], [http://www.ebi.ac.uk/pdbsum/4mqu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mqu ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/GCKR_HUMAN GCKR_HUMAN]] Inhibits glucokinase by forming an inactive complex with this enzyme.
+
[https://www.uniprot.org/uniprot/GCKR_HUMAN GCKR_HUMAN] Inhibits glucokinase by forming an inactive complex with this enzyme.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 27: Line 25:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Ashton, K S]]
+
[[Category: Ashton KS]]
-
[[Category: Bartberger, M D]]
+
[[Category: Bartberger MD]]
-
[[Category: Chen, J]]
+
[[Category: Chen J]]
-
[[Category: Chmait, S]]
+
[[Category: Chmait S]]
-
[[Category: Cupples, R]]
+
[[Category: Cupples R]]
-
[[Category: Galbreath, E]]
+
[[Category: Galbreath E]]
-
[[Category: Helmering, J]]
+
[[Category: Helmering J]]
-
[[Category: Jean, D J.St]]
+
[[Category: Jordan SR]]
-
[[Category: Jordan, S R]]
+
[[Category: Liu L]]
-
[[Category: Liu, L]]
+
[[Category: St Jean DJ]]
-
[[Category: Binds fructose phosphates and glucokinase]]
+
-
[[Category: Regulatory protein]]
+
-
[[Category: Sis domain]]
+
-
[[Category: Transferase inhibitor]]
+

Revision as of 10:02, 28 December 2022

Human GKRP complexed to AMG-3969 and S6P

PDB ID 4mqu

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4mqu"
Personal tools