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6cnh

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Human PRPF4B in complex with Rebastinib

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Retrieved from "http://52.214.119.220/wiki/index.php/6cnh"

@@ Line 3: / Line 3: @@
 <StructureSection load='6cnh' size='340' side='right'caption='[[6cnh]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6cnh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CNH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CNH FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6cnh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CNH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CNH FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=919:4-[4-({[3-TERT-BUTYL-1-(QUINOLIN-6-YL)-1H-PYRAZOL-5-YL]CARBAMOYL}AMINO)-3-FLUOROPHENOXY]-N-METHYLPYRIDINE-2-CARBOXAMIDE'>919</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=919:4-[4-({[3-TERT-BUTYL-1-(QUINOLIN-6-YL)-1H-PYRAZOL-5-YL]CARBAMOYL}AMINO)-3-FLUOROPHENOXY]-N-METHYLPYRIDINE-2-CARBOXAMIDE'>919</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cnh OCA], [https://pdbe.org/6cnh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cnh RCSB], [https://www.ebi.ac.uk/pdbsum/6cnh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cnh ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cnh OCA], [http://pdbe.org/6cnh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cnh RCSB], [http://www.ebi.ac.uk/pdbsum/6cnh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cnh ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/PRP4B_HUMAN PRP4B_HUMAN]] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.
+[https://www.uniprot.org/uniprot/PRP4B_HUMAN PRP4B_HUMAN] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Non-specific serine/threonine protein kinase]]
+[[Category: Arruda P]]
-[[Category: Arruda, P]]
+[[Category: Counago RM]]
-[[Category: Counago, R M]]
+[[Category: Edwards AM]]
-[[Category: Edwards, A M]]
+[[Category: Elkins JM]]
-[[Category: Elkins, J M]]
+[[Category: Fala AM]]
-[[Category: Fala, A M]]
+[[Category: Gileadi O]]
-[[Category: Gileadi, O]]
+[[Category: Godoi PHC]]
-[[Category: Godoi, P H.C]]
+[[Category: Guimaraes CRW]]
-[[Category: Guimaraes, C R.W]]
+[[Category: Massirer KB]]
-[[Category: Massirer, K B]]
+[[Category: Ramos PZ]]
-[[Category: Ramos, P Z]]
+[[Category: Righetto GL]]
-[[Category: Righetto, G L]]
+[[Category: Salmazo APT]]
-[[Category: Structural genomic]]
+[[Category: Santiago AS]]
-[[Category: Salmazo, A P.T]]
+[[Category: Silva PNB]]
-[[Category: Santiago, A S]]
-[[Category: Silva, P N.B]]
-[[Category: Dcc2036]]
-[[Category: Inhibitor]]
-[[Category: Kinase]]
-[[Category: Sgc]]
-[[Category: Transferase]]

6cnh

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Human PRPF4B in complex with Rebastinib

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