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6dwe
From Proteopedia
(Difference between revisions)
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<StructureSection load='6dwe' size='340' side='right'caption='[[6dwe]], [[Resolution|resolution]] 2.69Å' scene=''> | <StructureSection load='6dwe' size='340' side='right'caption='[[6dwe]], [[Resolution|resolution]] 2.69Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6dwe]] is a 8 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[6dwe]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DWE FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=HDJ:(2R,3S,4R)-3-(2,6-difluoro-4-methyl[1,1-biphenyl]-4-yl)-4-(fluoromethyl)azetidine-2-carbonitrile'>HDJ</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=P1T:2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC+ACID'>P1T</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.691Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=HDJ:(2R,3S,4R)-3-(2,6-difluoro-4-methyl[1,1-biphenyl]-4-yl)-4-(fluoromethyl)azetidine-2-carbonitrile'>HDJ</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=P1T:2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC+ACID'>P1T</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dwe OCA], [https://pdbe.org/6dwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dwe RCSB], [https://www.ebi.ac.uk/pdbsum/6dwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dwe ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/TRPA_MYCTU TRPA_MYCTU] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. |
==See Also== | ==See Also== | ||
| - | *[[Tryptophan synthase|Tryptophan synthase]] | + | *[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mycobacterium tuberculosis H37Rv]] |
| - | + | [[Category: Chang C]] | |
| - | + | [[Category: Jedrzejczak R]] | |
| - | [[Category: Chang | + | [[Category: Joachimiak A]] |
| - | [[Category: Jedrzejczak | + | [[Category: Maltseva NI]] |
| - | [[Category: Joachimiak | + | [[Category: McCarren P]] |
| - | [[Category: Maltseva | + | [[Category: Michalska K]] |
| - | [[Category: McCarren | + | [[Category: Nag PP]] |
| - | [[Category: Michalska | + | [[Category: Satchell K]] |
| - | [[Category: Nag | + | |
| - | [[Category: Satchell | + | |
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Current revision
Crystal structure of tryptophan synthase from M. tuberculosis - aminoacrylate- and BRD0059-bound form
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