This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4px5
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='4px5' size='340' side='right'caption='[[4px5]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='4px5' size='340' side='right'caption='[[4px5]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4px5]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4px5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PX5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PX5 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2WZ:N-[(R)-(2-AMINO-5-CHLORO-3-FLUOROPYRIDIN-4-YL){7-[4-(2-HYDROXYPROPAN-2-YL)PYRIDIN-2-YL]-1-BENZOTHIOPHEN-2-YL}METHYL]CYCLOPROPANESULFONAMIDE'>2WZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2WZ:N-[(R)-(2-AMINO-5-CHLORO-3-FLUOROPYRIDIN-4-YL){7-[4-(2-HYDROXYPROPAN-2-YL)PYRIDIN-2-YL]-1-BENZOTHIOPHEN-2-YL}METHYL]CYCLOPROPANESULFONAMIDE'>2WZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4px5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4px5 OCA], [https://pdbe.org/4px5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4px5 RCSB], [https://www.ebi.ac.uk/pdbsum/4px5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4px5 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/GCKR_HUMAN GCKR_HUMAN] Inhibits glucokinase by forming an inactive complex with this enzyme. |
==See Also== | ==See Also== | ||
| Line 15: | Line 14: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Chmait | + | [[Category: Chmait S]] |
| - | [[Category: Jordan | + | [[Category: Jordan SR]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 07:35, 8 February 2023
Human GKRP bound to AMG-0696 and Sorbitol-6-phosphate
| |||||||||||
