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4px3
From Proteopedia
(Difference between revisions)
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<StructureSection load='4px3' size='340' side='right'caption='[[4px3]], [[Resolution|resolution]] 2.43Å' scene=''> | <StructureSection load='4px3' size='340' side='right'caption='[[4px3]], [[Resolution|resolution]] 2.43Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4px3]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4px3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PX3 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2WX:N-[(R)-1-BENZOTHIOPHEN-2-YL(2-CHLOROPHENYL)METHYL]-3,4-DIHYDRO-2H-1,5-BENZODIOXEPINE-7-SULFONAMIDE'>2WX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2WX:N-[(R)-1-BENZOTHIOPHEN-2-YL(2-CHLOROPHENYL)METHYL]-3,4-DIHYDRO-2H-1,5-BENZODIOXEPINE-7-SULFONAMIDE'>2WX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4px3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4px3 OCA], [https://pdbe.org/4px3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4px3 RCSB], [https://www.ebi.ac.uk/pdbsum/4px3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4px3 ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/GCKR_HUMAN GCKR_HUMAN] Inhibits glucokinase by forming an inactive complex with this enzyme. |
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Chmait | + | [[Category: Chmait S]] |
| - | [[Category: Jordan | + | [[Category: Jordan SR]] |
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 07:35, 8 February 2023
Human GKRP bound to AMG-3295 and Sorbitol-6-phosphate
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