2ito

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caption="2ito, resolution 3.25Å" />
caption="2ito, resolution 3.25Å" />
'''CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN G719S MUTATION IN COMPLEX WITH IRESSA'''<br />
'''CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN G719S MUTATION IN COMPLEX WITH IRESSA'''<br />
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==Disease==
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Known diseases associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]], Nonsmall cell lung cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]]
==About this Structure==
==About this Structure==
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[[Category: zd1839]]
[[Category: zd1839]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 5 18:16:17 2007''
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 22:47:45 2007''

Revision as of 20:41, 12 November 2007

Image:2ito.gif

2ito, resolution 3.25Å

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CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN G719S MUTATION IN COMPLEX WITH IRESSA

Disease

Known diseases associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]

About this Structure

2ITO is a Single protein structure of sequence from Homo sapiens with IRE as ligand. Active as Receptor protein-tyrosine kinase, with EC number 2.7.10.1 Structure known Active Site: AC1. Full crystallographic information is available from OCA.

Page seeded by OCA on Mon Nov 12 22:47:45 2007

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