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5odd

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Current revision (10:22, 14 June 2023) (edit) (undo)
 
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==HUMAN MED26 N-TERMINAL DOMAIN (1-92)==
==HUMAN MED26 N-TERMINAL DOMAIN (1-92)==
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<StructureSection load='5odd' size='340' side='right'caption='[[5odd]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='5odd' size='340' side='right'caption='[[5odd]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5odd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2mzo 2mzo]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ODD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ODD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5odd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2mzo 2mzo]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ODD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ODD FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MED26, ARC70, CRSP7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5odd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5odd OCA], [https://pdbe.org/5odd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5odd RCSB], [https://www.ebi.ac.uk/pdbsum/5odd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5odd ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5odd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5odd OCA], [http://pdbe.org/5odd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5odd RCSB], [http://www.ebi.ac.uk/pdbsum/5odd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5odd ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MED26_HUMAN MED26_HUMAN]] Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.
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[https://www.uniprot.org/uniprot/MED26_HUMAN MED26_HUMAN] Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Cantrelle, F X]]
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[[Category: Cantrelle F-X]]
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[[Category: Dewitte, F]]
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[[Category: Dewitte F]]
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[[Category: Hanoulle, X]]
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[[Category: Hanoulle X]]
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[[Category: Landrieu, I]]
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[[Category: Landrieu I]]
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[[Category: Lens, Z]]
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[[Category: Lens Z]]
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[[Category: Perruzini, R]]
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[[Category: Perruzini R]]
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[[Category: Verger, A]]
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[[Category: Verger A]]
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[[Category: Villeret, V]]
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[[Category: Villeret V]]
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[[Category: Mediator complex transcriptional regulation]]
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[[Category: Transcription]]
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Current revision

HUMAN MED26 N-TERMINAL DOMAIN (1-92)

PDB ID 5odd

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