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6a3v

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Current revision (09:17, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6a3v' size='340' side='right'caption='[[6a3v]], [[Resolution|resolution]] 3.39&Aring;' scene=''>
<StructureSection load='6a3v' size='340' side='right'caption='[[6a3v]], [[Resolution|resolution]] 3.39&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6a3v]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A3V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6A3V FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6a3v]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6A3V FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.391&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TNFSF9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), TNFRSF9, CD137, ILA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6a3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a3v OCA], [http://pdbe.org/6a3v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6a3v RCSB], [http://www.ebi.ac.uk/pdbsum/6a3v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6a3v ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6a3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a3v OCA], [https://pdbe.org/6a3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6a3v RCSB], [https://www.ebi.ac.uk/pdbsum/6a3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6a3v ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TNFL9_HUMAN TNFL9_HUMAN]] Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. [[http://www.uniprot.org/uniprot/TNR9_HUMAN TNR9_HUMAN]] Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
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[https://www.uniprot.org/uniprot/TNFL9_HUMAN TNFL9_HUMAN] Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6a3v" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6a3v" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Tumor necrosis factor ligand superfamily 3D structures|Tumor necrosis factor ligand superfamily 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chai, Y]]
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[[Category: Chai Y]]
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[[Category: Gao, G F]]
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[[Category: Gao GF]]
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[[Category: Gao, S]]
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[[Category: Gao S]]
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[[Category: Li, Y]]
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[[Category: Li Y]]
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[[Category: Qi, J]]
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[[Category: Qi J]]
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[[Category: Tien, P]]
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[[Category: Tien P]]
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[[Category: Zhang, C]]
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[[Category: Zhang C]]
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[[Category: Agonist monoclonal antibody]]
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[[Category: Complex structure]]
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[[Category: Cross-linking]]
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[[Category: Immune system]]
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Current revision

Complex structure of human 4-1BB and 4-1BBL

PDB ID 6a3v

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