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4q9e

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<StructureSection load='4q9e' size='340' side='right'caption='[[4q9e]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
<StructureSection load='4q9e' size='340' side='right'caption='[[4q9e]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4q9e]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q9E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q9E FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4q9e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q9E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q9E FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene>, <scene name='pdbligand=XXH:4-NITROBENZALDEHYDE'>XXH</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene>, <scene name='pdbligand=XXH:4-NITROBENZALDEHYDE'>XXH</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3c2x|3c2x]], [[4q8s|4q8s]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q9e OCA], [https://pdbe.org/4q9e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q9e RCSB], [https://www.ebi.ac.uk/pdbsum/4q9e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q9e ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q9e OCA], [http://pdbe.org/4q9e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q9e RCSB], [http://www.ebi.ac.uk/pdbsum/4q9e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q9e ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR]] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).
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[https://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Camelus dromedarius]]
[[Category: Camelus dromedarius]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Kaur, P]]
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[[Category: Kaur P]]
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[[Category: Sharma, P]]
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[[Category: Sharma P]]
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[[Category: Sharma, S]]
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[[Category: Sharma S]]
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[[Category: Singh, T P]]
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[[Category: Singh TP]]
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[[Category: Sinha, M]]
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[[Category: Sinha M]]
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[[Category: Yadav, S P]]
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[[Category: Yadav SP]]
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[[Category: Yamini, S]]
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[[Category: Yamini S]]
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[[Category: Antibiotic]]
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[[Category: Antimicrobial]]
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[[Category: Immune response]]
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[[Category: Immune system]]
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[[Category: Peptidoglycan binding]]
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[[Category: Pgrp-]]
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[[Category: Secreted]]
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Revision as of 11:19, 15 February 2023

Structure of the ternary complex of peptidoglycan recognition protein, PGRP-S with N-acetyl glucosamine and paranitro benzaldehyde at 2.3 A resolution

PDB ID 4q9e

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